N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 676588-16-2; C11H15IN2O; molar mass 318.15 g/mol) is a halogenated pyridine building block used in chemical synthesis. The molecule combines an aryl iodide with a pivaloyl-protected 2-aminopyridine bearing a 6-methyl group, making it a versatile intermediate for cross-coupling and further functionalisation. Tech Serve Solutions supplies this heterocyclic reagent for research and development laboratories worldwide.
- Synonyms
- N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamideN-(5-Iodo-6-methylpyridin-2-yl)pivalamide2,2-Dimethyl-N-(5-iodo-6-methylpyridin-2-yl)propanamideN-(5-Iodo-6-methyl-2-pyridinyl)-2,2-dimethylpropanamideCAS 676588-16-2
Palladium-catalysed cross-coupling
The aryl iodide is a reactive handle for Suzuki, Sonogashira, Heck and related cross-coupling reactions. This allows controlled carbon-carbon bond formation at the 5-position of the pyridine ring.
Heterocyclic building block
As a substituted aminopyridine derivative, it serves as a scaffold for assembling more elaborate pyridine-containing structures in multistep synthesis. The defined substitution pattern supports regioselective elaboration.
Protected aminopyridine intermediate
The pivaloyl (2,2-dimethylpropionamide) group masks the 2-amino function during synthesis and can be removed under hydrolytic conditions to reveal the free amine. This makes the compound useful where amine protection is required.
Research and discovery chemistry
Halogenated heterocyclic building blocks of this type are widely used in medicinal and agrochemical discovery programmes to explore structure-activity relationships. It is supplied for laboratory research use.
| Molecular weight | 318.15 |
|---|---|
| Empirical formula | C11H15IN2O |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used as a halogenated pyridine building block in organic synthesis. The reactive aryl iodide makes it well suited to palladium-catalysed cross-coupling reactions, while the pivaloyl-protected aminopyridine core serves as a scaffold for preparing more complex heterocyclic compounds in research settings.
What is the CAS number and molecular formula of N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 676588-16-2. The empirical formula is C11H15IN2O (Hill notation) with a molecular weight of approximately 318.15 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a technical/research grade building block for laboratory and synthetic use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis can be provided on request so you can confirm assay and identity before purchase.
How should this compound be handled and stored?
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Handle it as a laboratory research chemical using good chemical hygiene: work in a well-ventilated area or fume hood, wear suitable gloves, eye protection and a lab coat, and avoid generating dust. Store in a tightly closed container in a cool, dry place away from incompatible materials. As detailed safety classification was not supplied with this listing, please refer to the Safety Data Sheet, which we provide with every order, before use.
How is N-(5-Iodo-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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The product is packed in appropriate laboratory-grade containers, sealed and labelled for safe transit, with pack sizes to suit research and development quantities. As an established exporter, Tech Serve Solutions arranges compliant international shipping with full documentation and a Safety Data Sheet supplied with each consignment.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, destination and intended use, and our team will respond with availability, lead time, specification and a quotation. Sample requests for evaluation can be accommodated subject to availability.
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