O,O′-Bis(trimethylsilyl)thymine
O,O′-Bis(trimethylsilyl)thymine (CAS: 7288-28-0) is a silylated pyrimidine derivative with a molecular weight of 270.48 g/mol. It serves as a versatile building block in organic synthesis, particularly for the preparation of modified nucleosides and heterocyclic compounds. This compound is a key intermediate in research and development, enabling access to complex molecular architectures within the pharmaceutical and chemical industries.
- Synonyms
- C11H22N2O2Si21,3-Bis(trimethylsilyl)thymine

Synthesis of Modified Nucleosides
O,O′-Bis(trimethylsilyl)thymine is employed as a precursor for synthesizing various modified thymidine analogues. These modifications are crucial in developing antiviral agents and in biochemical research.
Heterocyclic Compound Synthesis
This compound acts as a valuable building block for constructing diverse heterocyclic structures. Its silylated nature facilitates specific reaction pathways in medicinal chemistry and materials science.
Research and Development
Utilised in academic and industrial R&D settings, O,O′-Bis(trimethylsilyl)thymine aids in exploring novel chemical reactions and developing new synthetic methodologies for complex organic molecules.
| Molecular weight | 270.48 |
|---|---|
| Empirical formula | C11H22N2O2Si2 |
| Assay | 97% |
| Boiling point | 127-130 °C/18 mmHg(lit.) |
| Melting point | 73-75 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O,O′-Bis(trimethylsilyl)thymine used for?
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O,O′-Bis(trimethylsilyl)thymine is primarily used as a building block in organic synthesis, particularly for the preparation of modified nucleosides and heterocyclic compounds in research and development.
What are the CAS number and formula for O,O′-Bis(trimethylsilyl)thymine?
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The CAS number for O,O′-Bis(trimethylsilyl)thymine is 7288-28-0, and its empirical formula is C11H22N2O2Si2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O,O′-Bis(trimethylsilyl)thymine with an assay of 97%. This product is intended for research and chemical synthesis use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for O,O′-Bis(trimethylsilyl)thymine?
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O,O′-Bis(trimethylsilyl)thymine is classified under WGK 2 (German water hazard class). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing.
How is O,O′-Bis(trimethylsilyl)thymine packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample of O,O′-Bis(trimethylsilyl)thymine?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly with your inquiry.
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