Ethyltriphenylphosphonium bromide
Ethyltriphenylphosphonium bromide (CAS: 1530-32-1), with the molecular formula C20H18BrP and a molecular weight of 371.25 g/mol, is a vital Wittig reagent. It serves as a key reactant in various organic synthesis applications, particularly for C-C bond formation and olefination reactions. This compound is essential for creating complex organic molecules in research and industrial settings.
- IUPAC
- TEP
![Ethyltriphenylphosphonium bromide ([(C6H5)3P+C2H5]Br-) — chemical structure, CAS 1530-32-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1530-32-1.png&w=3840&q=75)
Synthesis of D-Amino Acids
Utilised as a reactant for the synthesis of D-amino acids, specifically derived from L-cysteine thiazolidines. This application is crucial in the production of specialised amino acid derivatives.
Olefination Reactions
Serves as a Wittig reagent for olefination reactions, contributing to the synthesis of complex molecules such as Leiodolide A. This facilitates the formation of carbon-carbon double bonds in intricate molecular structures.
Cycloalkanoindoline Synthesis
Employed in diastereoselective intramolecular imino-ene reactions for the synthesis of cycloalkanoindolines. This is important for constructing specific cyclic organic frameworks.
Maitotoxin Fragment Synthesis
A reactant in the coupling of key building blocks for the synthesis of the WXYZA′ domain of maitotoxin, showcasing its utility in complex natural product synthesis.
Polycondensation Reactions
Used in solid-state metathesis polycondensation to form alkyl-dipropenylthiophene monomers, enabling the creation of novel polymer building blocks.
| Molecular weight | 371.25 |
|---|---|
| Linear formula | [(C6H5)3P+C2H5]Br- |
| Assay | 99% |
| Application | Reactant for synthesis of: • D-amino acids from L-cysteine-derived thiazolidines1• Leiodolide A via aldol reactions and Horner-Wadsworth-Emmons olefination2• Cycloalkanoindolines via diastereoselective intramolecular inimo-ene reactions3• WXYZA′ domain of maitotoxin using the coupling of key building blocks4Reactant for: • Solid-state metathesis polycondensation to form alkyl-dipropenylthiophene monomers5• Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization / lactonization cyclization reactions for synthesis of an ABC ring system6 |
| Melting point | 203-205 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >200 °C / >392 °F |
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-51/53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyltriphenylphosphonium bromide used for?
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Ethyltriphenylphosphonium bromide is primarily used as a Wittig reagent in organic synthesis for C-C bond formation and olefination reactions, including the synthesis of D-amino acids, complex natural products, and specialised monomers.
What is the CAS number and formula for Ethyltriphenylphosphonium bromide?
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The CAS number is 1530-32-1, and its linear formula is [(C6H5)3P+C2H5]Br-.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyltriphenylphosphonium bromide with a minimum assay of 99%. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or any other pharmacopoeia, nutraceutical, or food applications unless explicitly stated.
How should Ethyltriphenylphosphonium bromide be handled safely?
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Ethyltriphenylphosphonium bromide is classified as toxic if swallowed and toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, face shields, and gloves. Ensure good ventilation and avoid release into the environment. It has a high flash point, over 200 °C.
Is Ethyltriphenylphosphonium bromide packed and exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Ethyltriphenylphosphonium bromide, and can cater to international shipping requirements.
How can I request a sample or quote for Ethyltriphenylphosphonium bromide?
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To request a sample or quote, please contact our sales team through the website or by direct inquiry, providing your details and the required quantity.
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