2,2′,4′-Trichloroacetophenone
2,2′,4′-Trichloroacetophenone (CAS: 4252-78-2) is an organic compound with the linear formula Cl₂C₆H₃COCH₂Cl and a molecular weight of 223.48 g/mol. As a chlorinated acetophenone derivative, it serves as a valuable intermediate in chemical synthesis. It is primarily utilised as a building block in organic chemistry for the creation of more complex molecules, particularly within the pharmaceutical and fine chemical sectors.
- IUPAC
- ω,2,4-Trichloroacetophenone,2,4-Dichlorophenacyl chloride
- Synonyms
- 4252-78-2Cl2C6H3COCH2Clω,2,4-Trichloroacetophenone2,4-Dichlorophenacyl chloride
Organic Synthesis Intermediate
This compound functions as a key building block in the synthesis of diverse organic molecules. Its reactive chloroacetyl and trichlorophenyl groups allow for various transformations in multi-step synthetic pathways.
Pharmaceutical Research
2,2′,4′-Trichloroacetophenone is employed in research and development for the synthesis of potential pharmaceutical agents and drug candidates. It can be incorporated into molecular structures to explore new therapeutic properties.
Fine Chemical Manufacturing
It is used in the production of specialised fine chemicals, leveraging its unique structural features for targeted applications in materials science or agrochemicals.
| Molecular weight | 223.48 |
|---|---|
| Linear formula | Cl2C6H3COCH2Cl |
| Assay | 97% |
| Boiling point | 130-135 °C/4 mmHg(lit.) |
| Melting point | 47-54 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2′,4′-Trichloroacetophenone used for?
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2,2′,4′-Trichloroacetophenone is primarily used as an intermediate and building block in organic synthesis, particularly for pharmaceutical and fine chemical research and manufacturing.
What is the CAS number and molecular formula for 2,2′,4′-Trichloroacetophenone?
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The CAS number is 4252-78-2 and the linear formula is Cl₂C₆H₃COCH₂Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2′,4′-Trichloroacetophenone with a minimum assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 2,2′,4′-Trichloroacetophenone be handled safely?
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Handling requires caution due to its hazardous properties. Use a dust mask (N95), safety eyeshields, face shields, and gloves. Ensure adequate ventilation to avoid respiratory irritation. Refer to the Safety Data Sheet for comprehensive guidance.
How is 2,2′,4′-Trichloroacetophenone packed and shipped?
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Products are carefully packed according to international shipping regulations. We export globally, ensuring compliance with all relevant transport directives.
How can I request a quote or sample for 2,2′,4′-Trichloroacetophenone?
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Please contact our sales department via the website or direct email to request a quotation or a product sample.
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