Pifithrin-α

CAS 63208-82-2C16H18N2OS·HBrCell Biology

Pifithrin-α (CAS: 63208-82-2), with the molecular formula C16H18N2OS·HBr and a molecular weight of 367.30 g/mol, is supplied by TSS as an off-white powder. This compound is recognised for its role as an inhibitor of p53-dependent apoptosis. It finds utility in various biological research applications, particularly in cancer research, cell biology, and studies concerning apoptosis and cell signalling.

IUPAC: 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide,PFT-α
Synonyms: PFT-α

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Pifithrin-α (C16H18N2OS·HBr) — chemical structure, CAS 63208-82-2; Life Science, fine chemical supplied by Tech Serve Solutions

Antitumor AgentsApoptosis InhibitorsApoptosis and Cell CycleBioactive Small MoleculesCancer ResearchCell BiologyInhibitorsTherapy Adjuncts More...

01 /Applications

Apoptosis Inhibition Research

Pifithrin-α is a key research chemical for investigating the mechanisms of apoptosis, specifically its role as a p53-dependent apoptosis inhibitor. It aids in understanding cellular programmed death pathways.

Cancer Research Studies

Utilised in cancer research, Pifithrin-α helps scientists explore therapeutic strategies targeting apoptosis evasion in cancer cells. Its application contributes to the development of novel anti-tumour agents.

Cell Biology and Signalling

This compound serves as a valuable tool in cell biology research, facilitating studies on cell cycle regulation and intracellular signalling pathways, particularly those influenced by p53.

02 /Properties

Molecular weight	367.30
Linear formula	C16H18N2OS·HBr
Assay	≥95% (HPLC)
Form	powder
Colour	off-white
Solubility	DMSO: soluble20 mg/mL
Storage temperature	−20°C
Melting point	192.1-192.5 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

63208-82-2

MDL number

MFCD00417851

PubChem substance

24898529

05 /Additional specifications

Shipped In	wet ice
Storage Condition	protect from light

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Pifithrin-α used for?

Pifithrin-α is primarily used in research settings for its role as an inhibitor of p53-dependent apoptosis. It is employed in studies related to cancer research, cell biology, and cell signalling.

What is the CAS number and molecular formula for Pifithrin-α?

The CAS number for Pifithrin-α is 63208-82-2, and its molecular formula is C16H18N2OS·HBr.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Pifithrin-α with an assay of ≥95% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Pifithrin-α be handled and stored?

Handling Pifithrin-α requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It should be stored at -20°C, protected from light, and is shipped on wet ice.

What is the physical form and colour of Pifithrin-α?

Pifithrin-α is supplied as an off-white powder.

How is Pifithrin-α shipped and exported?

Pifithrin-α is shipped on wet ice to maintain its stability. As a global supplier and exporter, TSS adheres to all necessary regulations for international shipment.