Picrotoxin
Picrotoxin (CAS: 124-87-8), a complex organic compound with the formula C30H34O13 and a molecular weight of 602.58 g/mol, is a potent neurotoxin. It acts as a non-competitive antagonist of GABA-A receptors, leading to central nervous system excitation. This white to light yellow powder is primarily used in scientific research for studying neurotransmission and ion channel function. It is available from Tech Serve Solutions for laboratory and research purposes.
- IUPAC
- Cocculin
Neuroscience Research
Picrotoxin is widely employed in neuroscience to investigate the function of GABA-A receptors and their role in neuronal excitability and synaptic transmission. Its antagonist properties allow researchers to probe the mechanisms of inhibitory neurotransmission.
Ion Channel Studies
As a modulator of ligand-gated ion channels, Picrotoxin is valuable for studying the structure and function of these critical cellular components. It helps elucidate the binding sites and mechanisms of channel gating.
Pharmacological Tool
In pharmacology, Picrotoxin serves as a standard tool for characterizing GABAergic pathways and for understanding the effects of substances that interact with these systems. Its well-defined mechanism of action makes it a reliable research probe.
| Molecular weight | 602.58 |
|---|---|
| Empirical formula | C30H34O13 |
| Form | powder |
| Colour | white to light yellow |
| Melting point | 203 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28 |
| Safety statements (S) | 28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Picrotoxin used for?
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Picrotoxin is primarily used in scientific research as a non-competitive antagonist of GABA-A receptors to study neurotransmission, ion channel function, and the mechanisms of central nervous system excitation.
What is the CAS number and formula for Picrotoxin?
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The CAS number for Picrotoxin is 124-87-8, and its empirical formula is C30H34O13.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Picrotoxin as a research-grade chemical. We do not represent it as USP, BP, or EP grade. Please refer to the product specifications for detailed purity information or contact us for a Certificate of Analysis.
How should Picrotoxin be handled safely?
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Picrotoxin is highly toxic (GHS06, Danger, H300). Handle with extreme caution using appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 or P3 filters). Ensure adequate ventilation and avoid ingestion, inhalation, and skin contact. Consult the Safety Data Sheet (SDS) before use.
How is Picrotoxin packed, shipped, and exported?
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Tech Serve Solutions packs and ships Picrotoxin according to international regulations for hazardous materials. As an experienced global supplier, we manage the export of chemicals worldwide, ensuring compliance with all relevant shipping and customs requirements.
How can I request a sample or quote for Picrotoxin?
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To request a sample or a quotation for Picrotoxin, please use the contact form on our website or reach out to our sales team directly with your inquiry, specifying the CAS number (124-87-8) and desired quantity.
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