Phenylmagnesium chloride solution
Phenylmagnesium chloride solution (CAS: 100-59-4, C6H5MgCl, MW: 136.86) is a vital organometallic reagent, commonly known as a Grignard reagent. Supplied as a technical grade solution at 1.0 M in 2-methyltetrahydrofuran, it is primarily utilized in organic synthesis for carbon-carbon bond formation. Its reactivity makes it indispensable in creating complex molecules across various chemical sectors.
Organic Synthesis
As a potent nucleophile, phenylmagnesium chloride solution is widely employed in the synthesis of complex organic molecules. It facilitates the formation of new carbon-carbon bonds through reactions with electrophiles such as aldehydes, ketones, esters, and epoxides.
Pharmaceutical Intermediates
This Grignard reagent is instrumental in the multi-step synthesis of various pharmaceutical intermediates. Its ability to introduce phenyl groups is crucial for building the carbon skeletons of many active pharmaceutical ingredients (APIs).
Fine Chemical Production
The chemical industry leverages phenylmagnesium chloride solution for the production of fine chemicals, including specialty polymers and advanced materials. Its controlled reactivity allows for precise molecular construction.
| Molecular weight | 136.86 |
|---|---|
| Linear formula | C6H5MgCl |
| Grade | technical |
| Density | ~1.02 g/mL at 20 °C0.911 at 25 °C |
| Concentration | 1.0 M in 2-methyltetrahydrofuran |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylmagnesium chloride solution used for?
+
Phenylmagnesium chloride solution is a Grignard reagent primarily used in organic synthesis for forming carbon-carbon bonds. It is essential in the production of pharmaceutical intermediates and fine chemicals.
What are the CAS number and formula for Phenylmagnesium chloride solution?
+
The CAS number is 100-59-4 and the linear formula is C6H5MgCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Phenylmagnesium chloride solution in technical grade, at a concentration of 1.0 M in 2-methyltetrahydrofuran. We do not represent this product as USP, BP, or EP grade.
How should Phenylmagnesium chloride solution be handled and stored?
+
Phenylmagnesium chloride solution is flammable and corrosive, and may form explosive peroxides. Handle with extreme care in a well-ventilated area, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Store refrigerated between 2-8°C, away from ignition sources and incompatible materials.
Is Phenylmagnesium chloride solution shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Phenylmagnesium chloride solution.
How can I request a sample or quote for Phenylmagnesium chloride solution?
+
To request a sample or obtain a quote for Phenylmagnesium chloride solution, please contact our sales department through the website or call us directly.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis