Phenylhydrazine
Phenylhydrazine (CAS: 100-63-0) is an organic compound with the linear formula C<sub>6</sub>H<sub>5</sub>NHNH<sub>2</sub> and a molecular weight of 108.14 g/mol. This liquid is a versatile building block in chemical synthesis, notably used in the production of chromophores and in various analytical techniques. Its applications span organic synthesis, glycobiology, and proteomics, making it a valuable reagent for research and industrial applications.
- Synonyms
- 1-HydrazinobenzenePhenylhydrazinHydrazine, phenyl-BenzenehydrazinePhenylhydrazideAzimene
Organic Synthesis
Phenylhydrazine serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, dyes, and agrochemicals. It is widely employed in Fischer indole synthesis and the preparation of pyrazoles.
Analytical Chemistry
It is used as a reagent for the detection and quantification of carbonyl compounds, particularly aldehydes and ketones, by forming characteristic phenylhydrazones. This application is crucial in various analytical and quality control procedures.
Glycobiology and Proteomics
Phenylhydrazine is utilised in glycan labelling and analysis, contributing to the study of complex carbohydrates. Its role extends to post-translational modification analysis within proteomics research.
Chromophore Development
The compound is a precursor for synthesising molecules that absorb and emit light, finding application in the development of chromophores for dyes and indicators.
| Molecular weight | 108.14 |
|---|---|
| Linear formula | C6H5NHNH2 |
| Assay | ≥95.0% (GC) |
| Boiling point | 238-241 °C(lit.) |
| Density | 1.098 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.607(lit.) |
| Vapour pressure | <0.1 mmHg (20 °C) |
| Melting point | 18-21 °C(lit.) |
| Vapour density | 4.3 (vs air) |
| Autoignition temp | 345 °F |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H341Suspected of causing genetic defects
- H350May cause cancer
- H372Causes damage to organs through prolonged exposure
- H400Very toxic to aquatic life
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | UN 2572 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 45-23/24/25-36/38-43-48/23/24/25-50-68 |
| Safety statements (S) | 53-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylhydrazine used for?
+
Phenylhydrazine is used as a building block in organic synthesis, for detecting carbonyl compounds, in glycobiology and proteomics research, and for developing chromophores.
What are the CAS number and formula for Phenylhydrazine?
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The CAS number for Phenylhydrazine is 100-63-0, and its linear formula is C₆H₅NHNH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylhydrazine with an assay of ≥95.0% (GC). This product is suitable for research and chemical synthesis and is not represented as USP, BP, or EP grade.
What are the primary hazards associated with Phenylhydrazine?
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Phenylhydrazine is a Danger signal word chemical. It is toxic if swallowed, in contact with skin, or if inhaled (H301, H311, H331). It can cause skin irritation (H315), skin sensitisation (H317), serious eye irritation (H319), and is suspected of causing genetic defects (H341) and cancer (H350). It can also cause damage to organs through prolonged or repeated exposure (H372) and is very toxic to aquatic life (H400).
How is Phenylhydrazine packed and shipped?
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Phenylhydrazine is typically packed in appropriate containers to ensure safety and integrity during transport. It is classified under UN 2572, Class 6.1, Packing Group II, for transportation.
How can I request a quote or sample for Phenylhydrazine?
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To request a quote or sample of Phenylhydrazine, please contact our sales team through the website or by phone, providing your details and the quantity required.
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