(+)-Biotin hydrazide
(+)-Biotin hydrazide (CAS 66640-86-6) is a chemical compound with the formula C10H18N4O2S and a molecular weight of 258.34 g/mol. This reagent is primarily utilized for labeling biologically active molecules. It facilitates conjugation by reacting with aldehyde groups, particularly useful for modifying glycoproteins through hydrazone formation via their carbohydrate moieties. (+)-Biotin hydrazide is supplied by Tech Serve Solutions for research and development purposes.
Bioconjugation
(+)-Biotin hydrazide is employed to conjugate biotin to various biomolecules. It reacts efficiently with aldehyde-functionalized molecules, enabling the creation of biotinylated targets for downstream detection or purification.
Glycoprotein Labeling
This reagent is particularly effective for labeling glycoproteins. It reacts with the carbohydrate portions of glycoproteins that have been oxidized to aldehydes, allowing for specific biotinylation.
Antibody Modification
Antibodies can be modified with (+)-Biotin hydrazide, especially if they possess or can be derivatized to possess aldehyde functionalities, enhancing their utility in immunoassay systems.
Nucleic Acid Labeling
Nucleic acids, after suitable chemical modification to introduce aldehyde groups, can be labeled with (+)-Biotin hydrazide for applications in molecular biology and diagnostics.
| Molecular weight | 258.34 |
|---|---|
| Empirical formula | C10H18N4O2S |
| Assay | ≥97% (TLC) |
| Form | powder |
| Solubility | DMSO: ≤20 mg/mL |
| Optical activity | [α]20/D +68±3°, c = 0.5% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 245-247 °C |
| Application | Reagent for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone formation. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-Biotin hydrazide used for?
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(+)-Biotin hydrazide is a reagent used for labeling biologically active molecules such as antibodies, lectins, sugars, and nucleic acids. It is particularly useful for labeling glycoproteins through hydrazone formation with aldehyde groups on the carbohydrate moiety.
What are the CAS number and formula for (+)-Biotin hydrazide?
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The CAS number for (+)-Biotin hydrazide is 66640-86-6, and its empirical formula is C10H18N4O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-Biotin hydrazide with a purity of ≥97% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should (+)-Biotin hydrazide be handled safely?
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When handling (+)-Biotin hydrazide, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The material is classified with WGK Germany 3, indicating it is hazardous to water.
How is (+)-Biotin hydrazide packed, shipped, and exported?
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(+)-Biotin hydrazide is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for (+)-Biotin hydrazide?
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To request a sample or a quotation for (+)-Biotin hydrazide, please contact the Tech Serve Solutions sales team through our official channels.
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