5-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde

CAS 98700-50-6C11H10N2OChemical Synthesis

5-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde (CAS: 98700-50-6) is an organic compound with the molecular formula C11H10N2O and a molecular weight of 186.21 g/mol. This pyrazole derivative functions as a key intermediate in organic synthesis. It is primarily utilised as a reactant in the preparation of various pharmacologically active compounds, including potential Smoothened antagonists and ORL1 receptor antagonists, as well as novel dialkylamino(phenyl-1H-pyrazolyl)butanols.

IUPAC: 4-Formyl-5-methyl-1-phenylpyrazole,5-Methyl-1-phenyl-4-pyrazolecarboxaldehyde
Synonyms: 4-Formyl-5-methyl-1-phenylpyrazole5-Methyl-1-phenyl-4-pyrazolecarboxaldehyde

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5-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde (C11H10N2O) — chemical structure, CAS 98700-50-6; Chemistry, fine chemical supplied by Tech Serve Solutions

AldehydesBuilding BlocksC10-C12Carbonyl CompoundsChemical Synthesis

01 /Applications

Synthesis of (Aminomethyl)pyrazoles

This aldehyde serves as a precursor in the reductive amination to synthesise (aminomethyl)pyrazoles. These compounds have been explored for their potential as Smoothened antagonists, relevant in hair inhibition research.

Development of ORL1 Receptor Antagonists

The compound is employed in the synthesis of novel ORL1 receptor antagonists. Specifically, it is used in the preparation of N-biarylmethyl spiropiperidine derivatives with potential therapeutic applications.

Preparation of Dialkylamino(phenyl-1H-pyrazolyl)butanols

It acts as a starting material for the preparation of pharmacologically active dialkylamino(phenyl-1H-pyrazolyl)butanols, contributing to the development of new chemical entities.

02 /Properties

Molecular weight	186.21
Empirical formula	C11H10N2O
Application	Reactant for:• Synthesis of (aminomethyl)pyrazoles by reductive amination as Smoothened antagonists for hair inhibition1• Synthesis of ORL1 receptor antagonists based on N-biarylmethyl spiropiperidine2• Preparation of pharmacologically active dialkylamino(phenyl-1H-pyrazolyl)butanols3
Melting point	73-78 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

98700-50-6

MDL number

MFCD02681920

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde used for?

This compound is primarily used as a reactant in organic synthesis for preparing pharmacologically active molecules, including (aminomethyl)pyrazoles for Smoothened antagonism and N-biarylmethyl spiropiperidine derivatives as ORL1 receptor antagonists.

What is the CAS number and molecular formula for 5-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde?

The CAS number is 98700-50-6, and the molecular formula is C11H10N2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity available can be confirmed by contacting our sales team. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for handling this chemical?

This compound is classified as harmful if swallowed (H302) and carries a Warning signal word. Appropriate personal protective equipment, including gloves and eye protection, should be worn, and handling should occur in a well-ventilated area.

Is this chemical available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped internationally subject to relevant regulations.

How can I request a sample or quote?

To request a sample or obtain a quote, please contact our customer service department via email or phone, providing the product name and CAS number (98700-50-6).