(+)-Biotin 4-nitrophenyl ester
(+)-Biotin 4-nitrophenyl ester (CAS: 33755-53-2; Formula: C16H19N3O5S) is a biotinylation reagent derived from Vitamin B7. It is a white to off-white crystalline solid with a molecular weight of 365.40 g/mol. This ester is primarily utilised in chemical synthesis and biochemical research as a convenient precursor for introducing biotinyl groups onto other molecules. Its utility spans areas like asymmetric synthesis and cell biology studies.
- IUPAC
- 4-Nitrophenyl (+)-biotinate,d-Biotin p-nitrophenyl ester,BNP
- Synonyms
- 4-Nitrophenyl (+)-biotinated-Biotin p-nitrophenyl esterBNP
Chemical Synthesis
(+)-Biotin 4-nitrophenyl ester serves as a key intermediate in organic synthesis. It allows for the controlled introduction of the biotin moiety into more complex molecular structures, facilitating the creation of novel compounds for research and development.
Biochemical Research
In cell biology and biochemistry, this compound is employed for biotinylation of proteins and other biomolecules. This labelling enables detection, purification, and study of biological interactions through the high affinity between biotin and avidin/streptavidin.
Chiral Building Block
As a chiral molecule, it can be utilized in asymmetric synthesis, where stereochemistry is crucial for the biological activity or properties of the final product. It contributes to the construction of enantiomerically pure substances.
Nutrition Research
While primarily a research chemical, its relation to Vitamin B7 (biotin) means it can be indirectly involved in studies exploring biotin metabolism and its physiological roles.
| Molecular weight | 365.40 |
|---|---|
| Empirical formula | C16H19N3O5S |
| Assay | 98% |
| Solubility | methanol: soluble25 mg/mL, clear, colorless to greenish-yellow |
| Optical activity | [α]25/D +51°, c = 2 in DMF: AcOH (99:1) |
| Melting point | 163-165 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-Biotin 4-nitrophenyl ester used for?
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It is used in chemical synthesis and biochemical research for the biotinylation of molecules, acting as a chiral building block and in nutrition research contexts.
What is the CAS number and chemical formula for (+)-Biotin 4-nitrophenyl ester?
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The CAS number is 33755-53-2, and the chemical formula is C16H19N3O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling (+)-Biotin 4-nitrophenyl ester?
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Handling requires appropriate personal protective equipment including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound is classified under WGK Germany 3, indicating it is hazardous to water.
How is (+)-Biotin 4-nitrophenyl ester packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping and handling regulations for research and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team through the website to request a quote or a sample for (+)-Biotin 4-nitrophenyl ester.
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