(+)-Bis[(R)-1-phenylethyl]amine
(+)-Bis[(R)-1-phenylethyl]amine (CAS: 23294-41-9) is a chiral amine with the molecular formula [C6H5CH(CH3)]2NH and a molecular weight of 225.33 g/mol. It is characterised by its significant optical activity ([α]20/D +199.0°). This compound serves as a valuable building block in asymmetric synthesis, particularly for the preparation of chiral β-amino acids, contributing to the development of stereochemically pure compounds in research and development.
- IUPAC
- (+)-Bis[(R)-α-methylbenzyl]amine,[R-(R*,R*)]-(+)-Bis(α-methylbenzyl)amine
- Synonyms
- (+)-Bis[(R)-α-methylbenzyl]amine[R-(R*,R*)]-(+)-Bis(α-methylbenzyl)amine
![(+)-Bis[(R)-1-phenylethyl]amine ([C6H5CH(CH3)]2NH) — chemical structure, CAS 23294-41-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F23294-41-9.png&w=3840&q=75)
Chiral Synthesis
Utilised as a chiral amine in asymmetric synthesis for the preparation of enantiomerically enriched compounds, including β-amino acids. Its specific stereochemistry is crucial for directing the stereochemical outcome of reactions.
Organic Building Block
Serves as a key intermediate and building block in organic synthesis. Its structure allows for the introduction of chiral centres into more complex molecules, essential for pharmaceutical and fine chemical research.
Asymmetric Induction
Employed in methodologies requiring asymmetric induction, facilitating the synthesis of stereospecific target molecules where precise control of chirality is paramount.
| Molecular weight | 225.33 |
|---|---|
| Linear formula | [C6H5CH(CH3)]2NH |
| Assay | 99% |
| Boiling point | 86 °C/0.05 mmHg(lit.) |
| Density | 0.985 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5523(lit.) |
| Optical activity | [α]20/D +199.0°, neat |
| Optical purity | ee: ≥99% (GLC) |
| Application | Useful chiral amine for the synthesis of β-amino acids.1 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-Bis[(R)-1-phenylethyl]amine used for?
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(+)-Bis[(R)-1-phenylethyl]amine is primarily used as a chiral amine building block in asymmetric synthesis, notably for the preparation of β-amino acids and other stereochemically pure compounds.
What are the CAS number and formula for (+)-Bis[(R)-1-phenylethyl]amine?
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The CAS number is 23294-41-9 and the molecular formula is [C6H5CH(CH3)]2NH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-Bis[(R)-1-phenylethyl]amine with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (+)-Bis[(R)-1-phenylethyl]amine be handled?
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(+)-Bis[(R)-1-phenylethyl]amine is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Ensure adequate ventilation and avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
Is (+)-Bis[(R)-1-phenylethyl]amine a controlled substance?
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There is no information available in the provided data to indicate that (+)-Bis[(R)-1-phenylethyl]amine is a controlled substance.
How can I request a quote or sample?
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To request a quote or a sample of (+)-Bis[(R)-1-phenylethyl]amine, please contact our sales team via the website or provide your details through the online enquiry form.
How is this chemical packed and exported?
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This chemical is carefully packed according to industry standards to ensure safe transit and is exported globally by TSS. Specific packing configurations are available upon request.
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