(+)-Biotinamidohexanoic acid hydrazide
(+)-Biotinamidohexanoic acid hydrazide (CAS: 109276-34-8, C16H29N5O3S) is a valuable biotinylation reagent. It facilitates the conjugation of biotin to molecules containing aldehyde functionalities, such as periodate-oxidised carbohydrates. The compound features an aminocaproic acid spacer, allowing for effective coupling via hydrazone bond formation. This reagent is essential in various biochemical and molecular biology applications for protein and glycoprotein modification and detection.
- IUPAC
- (+)-Biotin-ε-aminocaproyl hydrazide,(+)-Biotin-X-hydrazide,(+)-Biotinamidocaproyl hydrazide,BACH,N-(+)-Biotinyl-6-aminohexanoic hydrazide
- Synonyms
- (+)-Biotin-ε-aminocaproyl hydrazide(+)-Biotin-X-hydrazide(+)-Biotinamidocaproyl hydrazideBACHN-(+)-Biotinyl-6-aminohexanoic hydrazide
Biotinylation of Aldehydes
(+)-Biotinamidohexanoic acid hydrazide reacts with aldehyde groups, commonly found in oxidised glycoproteins. This enables the selective labelling of target molecules with biotin.
Glycoprotein Detection
Its ability to form hydrazone bonds with oxidised sugars makes it ideal for detecting and analysing glycoproteins, particularly in techniques like Western blotting.
Bioconjugation
The molecule serves as a versatile linker for creating bioconjugates, coupling biotin to biomolecules through a stable hydrazone linkage after appropriate sample preparation.
Protein Structural Analysis
Used in proteomics and protein chemistry for modifications that aid in structural analysis and understanding post-translational modifications.
| Molecular weight | 371.50 |
|---|---|
| Empirical formula | C16H29N5O3S |
| Assay | ≥90% (TLC) |
| Form | powder |
| Solubility | DMSO: soluble25 mg/mL |
| Storage temperature | 2-8°C |
| Application | Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-Biotinamidohexanoic acid hydrazide used for?
+
(+)-Biotinamidohexanoic acid hydrazide is primarily used as a biotinylation reagent for molecules containing aldehyde groups, such as oxidised carbohydrates on glycoproteins. It facilitates the formation of stable hydrazone bonds for detection and analysis in biochemical and molecular biology research.
What are the CAS number and chemical formula?
+
The CAS number for (+)-Biotinamidohexanoic acid hydrazide is 109276-34-8, and its empirical formula is C16H29N5O3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-Biotinamidohexanoic acid hydrazide with an assay of ≥90% (TLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling considerations?
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This compound has a WGK Germany rating of 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling and safety information.
How is the product stored and shipped?
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The recommended storage temperature for (+)-Biotinamidohexanoic acid hydrazide is 2-8°C. It is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample?
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To request a quote or a sample of (+)-Biotinamidohexanoic acid hydrazide, please contact our sales team via the website or direct email, providing your specific requirements.
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