(+)-B-Methoxydiisopinocampheylborane
(+)-B-Methoxydiisopinocampheylborane (CAS: 99438-28-5; Formula: C21H37BO; MW: 316.33) is a chiral reagent utilised in asymmetric synthesis. It serves as a precursor for generating chiral organoborane derivatives, which are instrumental in the stereoselective synthesis of complex organic molecules, including homoallylic alcohols and beta-amino alcohols with high enantiomeric excess.
- IUPAC
- (+)-Diisopinocampheylmethoxyborane
- Synonyms
- (+)-Diisopinocampheylmethoxyborane
Precursor for Chiral Organoboranes
(+)-B-Methoxydiisopinocampheylborane is a valuable precursor for synthesising chiral organoborane derivatives, such as B-allyldiisopinocampheylborane. These derivatives are key intermediates in stereoselective transformations.
Synthesis of Homoallylic Alcohols
The derived B-allyldiisopinocampheylborane reacts with aldehydes to produce homoallylic alcohols. This reaction proceeds with high enantioselectivity, yielding products with significant optical purity.
Synthesis of Beta-Amino Alcohols
In a similar synthetic pathway, derivatives of (+)-B-Methoxydiisopinocampheylborane can be employed to synthesise enantiomerically enriched beta-amino alcohols. This broadens its utility in creating chiral building blocks for pharmaceuticals and fine chemicals.
| Molecular weight | 316.33 |
|---|---|
| Empirical formula | C21H37BO |
| Application | Both (+)- and (-)-forms are precursors to B-allyldiisopinocampheylborane derivatives, which are subsequently reacted with aldehydes to give homoallylic alcohols6 and β-amino alcohols7 of high enantiomeric excess.8 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-B-Methoxydiisopinocampheylborane used for?
+
(+)-B-Methoxydiisopinocampheylborane is used as a precursor in asymmetric synthesis for preparing chiral organoborane derivatives. These derivatives are then employed to synthesise enantiomerically enriched homoallylic alcohols and beta-amino alcohols.
What is the CAS number and formula for (+)-B-Methoxydiisopinocampheylborane?
+
The CAS number for (+)-B-Methoxydiisopinocampheylborane is 99438-28-5, and its molecular formula is C21H37BO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (+)-B-Methoxydiisopinocampheylborane in research grade. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (+)-B-Methoxydiisopinocampheylborane be handled safely?
+
Handle (+)-B-Methoxydiisopinocampheylborane with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. It is a warning substance that can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation.
Is (+)-B-Methoxydiisopinocampheylborane available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (+)-B-Methoxydiisopinocampheylborane, adhering to all relevant export regulations.
How can I request a sample or quote for (+)-B-Methoxydiisopinocampheylborane?
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To request a sample or a quotation for (+)-B-Methoxydiisopinocampheylborane, please contact our sales team through the website or by phone, providing your specific requirements.
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