Phenylglyoxal hydrate
Phenylglyoxal hydrate (CAS: 1075-06-5) is a carbonyl compound with the linear formula C6H5COCHO · xH2O and a molecular weight of 134.13 on an anhydrous basis. This organic building block is utilised in chemical synthesis for preparing various heterocyclic derivatives and as a specific reagent for modifying amino acid residues. Supplied at 97% purity, it serves as a valuable intermediate in research and development settings.
- IUPAC
- 2,2-Dihydroxyacetophenone
Reagent for Arginine Residues
Phenylglyoxal hydrate functions as a specific reagent for the modification of arginine groups in proteins and peptides. This reactivity is key in biochemical studies for understanding protein structure and function.
Synthesis of Heterocyclic Compounds
This compound is employed in the preparation of pyrrolinone and furan derivatives. These syntheses highlight its utility as a versatile building block in organic chemistry for creating novel molecular structures.
Chemiluminescent Detection
Phenylglyoxal hydrate has been utilised as a chemiluminescent reagent for the analytical determination of purines. This application demonstrates its potential in sensitive detection methods.
Enzyme Modification Studies
It has been used in studies to modify enzymes, such as pig muscle carbonic anhydrase III. Such modifications help elucidate enzyme mechanisms and active site characteristics.
| Molecular weight | 134.13 (anhydrous basis) |
|---|---|
| Linear formula | C6H5COCHO · xH2O |
| Assay | 97% |
| Boiling point | 142 °C/125 mmHg(lit.) |
| Solubility | 95% ethanol: soluble5%, clear to very slightly hazy, colorless to light yellow |
| Application | Phenylglyoxal hydrate was used :• to modify pig muscle carbonic anhydraseIII1 • as specific reagent for arginine groups2 • to prepare pyrrolinone3 and furan4 derivatives • as chemiluminescent reagent for the determination of purines5,6 |
| Melting point | 76-79 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylglyoxal hydrate used for?
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Phenylglyoxal hydrate is used as a specific reagent for arginine groups, in the preparation of pyrrolinone and furan derivatives, as a chemiluminescent reagent for purine determination, and for modifying enzymes like carbonic anhydrase III.
What is the CAS number and formula for Phenylglyoxal hydrate?
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The CAS number is 1075-06-5 and the linear formula is C6H5COCHO · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylglyoxal hydrate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling Phenylglyoxal hydrate?
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Phenylglyoxal hydrate is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (type N95), eye shields, face shields, and gloves, should be worn. Handle in a well-ventilated area and avoid breathing dust. Refer to the Safety Data Sheet for detailed information.
How is Phenylglyoxal hydrate packed, shipped, and exported?
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Tech Serve Solutions offers Phenylglyoxal hydrate in various quantities, packaged securely for safe transit. We are experienced global exporters of fine chemicals and laboratory reagents, adhering to international shipping regulations.
How can I request a quote or sample for Phenylglyoxal hydrate?
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To request a quote or sample for Phenylglyoxal hydrate, please contact our sales department via the website or telephone, providing your specific requirements.
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