Phenylboronic acid pinacol ester
Phenylboronic acid pinacol ester (CAS 24388-23-6, C12H17BO2) is a stable organoboron compound with a molecular weight of 204.07 g/mol. This aryl boronate ester is a key building block in organic synthesis, particularly favoured for its utility in cross-coupling reactions like the Suzuki-Miyaura coupling. It serves as a versatile reagent in the development of pharmaceuticals, agrochemicals, and advanced materials.
- IUPAC
- (Pinacolboryl)benzene,4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane,Pinacol phenylboronate,cyclic tetramethylethylene ester benzeneboronic acid
- Synonyms
- 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolanePinacol phenylboronatecyclic tetramethylethylene ester benzeneboronic acid(Pinacolboryl)benzene
Suzuki-Miyaura Coupling Reagent
This pinacol ester is widely employed in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds by reacting with aryl or vinyl halides. It is a crucial intermediate for synthesising complex organic molecules.
Organic Synthesis Intermediate
As a versatile building block, phenylboronic acid pinacol ester facilitates the introduction of phenyl groups into various molecular scaffolds. Its stability and reactivity profile make it ideal for multi-step synthetic pathways.
Pharmaceutical and Agrochemical Development
The compound is instrumental in the synthesis of active pharmaceutical ingredients (APIs) and agrochemical compounds. Its application contributes to the creation of novel therapeutic agents and crop protection solutions.
Materials Science
Phenylboronic acid pinacol ester finds application in the synthesis of functional materials, including organic light-emitting diodes (OLEDs) and polymers, due to its ability to form specific carbon frameworks.
| Molecular weight | 204.07 |
|---|---|
| Empirical formula | C12H17BO2 |
| Assay | 97% |
| Melting point | 27-31 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylboronic acid pinacol ester used for?
+
Phenylboronic acid pinacol ester is primarily used as a key reagent in Suzuki-Miyaura cross-coupling reactions for forming carbon-carbon bonds, and as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and molecular formula?
+
The CAS number for Phenylboronic acid pinacol ester is 24388-23-6, and its molecular formula is C12H17BO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Phenylboronic acid pinacol ester at a minimum assay of 97%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the safety and handling precautions for this compound?
+
This compound is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). When handling, use a dust mask (type N95 or equivalent), wear eyeshields and gloves, and ensure adequate ventilation. Avoid breathing dust. In case of contact, rinse cautiously with water. If inhaled, move to fresh air.
How is Phenylboronic acid pinacol ester packaged and shipped?
+
Phenylboronic acid pinacol ester is available in various pack sizes suitable for laboratory research and industrial export. TSS ensures secure packaging and compliance with international shipping regulations for chemical compounds.
How can I request a quote or sample?
+
To request a quote or sample of Phenylboronic acid pinacol ester, please contact our sales team via the website or direct email, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis