Phenylguanidine carbonate salt
Phenylguanidine carbonate salt (CAS: 14018-90-7) is an organic compound with the molecular formula C6H5NHC(=NH)NH2·(H2CO3)x and a molecular weight of 135.17. This guanidine derivative serves as a valuable building block in chemical synthesis. Its primary documented application involves its use as a reactant in the preparation of polo-like kinase 1 inhibitors, highlighting its role in medicinal chemistry research and development.

Synthesis of Polo-like Kinase 1 Inhibitors
Phenylguanidine carbonate salt is employed as a key reactant in the synthetic pathways leading to the development of polo-like kinase 1 (PLK1) inhibitors. These inhibitors are of significant interest in cancer research due to the role of PLK1 in cell cycle regulation.
Organic Synthesis Building Block
As a guanidine derivative, this compound functions as a versatile building block in organic synthesis. It can be incorporated into various molecular structures, enabling the creation of novel compounds with potential pharmaceutical or material science applications.
Research and Development Reagent
This chemical is utilised in research laboratories for exploring new synthetic methodologies and discovering novel chemical entities. Its defined structure and reactivity make it a useful tool for chemists investigating complex organic transformations.
| Molecular weight | 135.17 |
|---|---|
| Linear formula | C6H5NHC(=NH)NH2·(H2CO3)x |
| Assay | ≥99% |
| Application | Reactant involved in synthesis of polo-like kinase 1 inhibitors1 |
| Melting point | 149-153 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylguanidine carbonate salt used for?
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Phenylguanidine carbonate salt is used as a reactant in the synthesis of polo-like kinase 1 inhibitors and as a general building block in organic synthesis for research and development purposes.
What is the CAS number and formula for Phenylguanidine carbonate salt?
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The CAS number is 14018-90-7 and the molecular formula is C6H5NHC(=NH)NH2·(H2CO3)x.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylguanidine carbonate salt with an assay of ≥99%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations when handling Phenylguanidine carbonate salt?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany rating of 3, indicating it is hazardous.
How is Phenylguanidine carbonate salt packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and adherence to all shipping regulations for chemical products like Phenylguanidine carbonate salt.
How can I request a sample or quote for Phenylguanidine carbonate salt?
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To request a sample or a quote, please contact our sales department via the website or provided contact details, specifying the product name and CAS number.
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