Phenylmagnesium bromide solution
Phenylmagnesium bromide solution (CAS: 100-58-3, C6H5MgBr, MW: 181.31) is a crucial organometallic reagent supplied by Tech Serve Solutions. This aryl Grignard reagent, typically provided as a 1.0 M solution in Tetrahydrofuran (THF), is indispensable in organic synthesis for forming new carbon-carbon bonds. Its high reactivity makes it a valuable tool in academic research and industrial chemical manufacturing.
- Synonyms
- Phenylmagnesium bromide THF solutionPhenylmagnesium bromide, 1M in THF
Carbon-Carbon Bond Formation
As a potent Grignard reagent, Phenylmagnesium bromide is extensively used to introduce a phenyl group onto electrophilic carbon atoms in aldehydes, ketones, esters, and epoxides, facilitating the synthesis of complex organic molecules.
Synthesis of Pharmaceutical Intermediates
It serves as a key building block in the multi-step synthesis of various pharmaceutical intermediates, enabling the construction of complex molecular scaffolds required for drug discovery and development.
Organometallic Chemistry Research
Researchers utilise Phenylmagnesium bromide in academic and industrial settings to explore new reaction pathways, develop novel synthetic methodologies, and create advanced materials.
Catalysis and Material Science
While primarily a reagent, its derivatives can find applications in catalysis and material science, leveraging the unique electronic and steric properties of the phenyl group attached to magnesium.
| Molecular weight | 181.31 |
|---|---|
| Linear formula | C6H5MgBr |
| Density | 1.004 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -11 °C / 12.2 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylmagnesium bromide solution used for?
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Phenylmagnesium bromide solution is primarily used in organic synthesis for carbon-carbon bond formation, acting as a phenylating agent in reactions with various electrophiles like aldehydes, ketones, and esters. It is also a key intermediate in the synthesis of pharmaceuticals and fine chemicals.
What are the CAS number and formula for Phenylmagnesium bromide solution?
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The CAS number for Phenylmagnesium bromide solution is 100-58-3, and its linear formula is C6H5MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylmagnesium bromide solution at a concentration of 1.0 M in THF. We do not represent this product as USP, BP, or EP grade; it is suitable for research and industrial chemical synthesis.
How should Phenylmagnesium bromide solution be handled safely?
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Phenylmagnesium bromide solution is highly reactive and flammable. It reacts violently with water, is corrosive, and can form explosive peroxides. Handle it under an inert atmosphere, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Avoid ignition sources.
Is Phenylmagnesium bromide solution packed and shipped internationally?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Phenylmagnesium bromide solution, adhering to all relevant shipping and safety regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or a sample of Phenylmagnesium bromide solution, please use the 'Request Quote' or 'Request Sample' buttons on our product page, or contact our sales team directly with your requirements.
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