2-Amino-5-chloropyrimidine
2-Amino-5-chloropyrimidine (CAS: 5428-89-7), a halogenated pyrimidine derivative with the molecular formula C4H4ClN3 and a molecular weight of 129.55 g/mol, is a key heterocyclic building block. This compound is primarily utilised in chemical synthesis for the construction of more complex organic molecules, particularly within the pharmaceutical and agrochemical industries. Its structure makes it a valuable intermediate for creating novel chemical entities.

Pharmaceutical Intermediate
Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), contributing to the development of new therapeutic agents.
Agrochemical Synthesis
Employed as a precursor in the development of novel agrochemicals, including pesticides and herbicides, by providing a core pyrimidine structure.
Organic Synthesis Reagent
Utilised in academic and industrial research for its versatility in constructing a wide range of heterocyclic compounds due to its reactive amino and chloro functionalities.
| Molecular weight | 129.55 |
|---|---|
| Empirical formula | C4H4ClN3 |
| Assay | 97% |
| Melting point | 235-238 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-chloropyrimidine used for?
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2-Amino-5-chloropyrimidine (CAS: 5428-89-7) is primarily used as a building block in chemical synthesis, particularly for pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for 2-Amino-5-chloropyrimidine?
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The CAS number is 5428-89-7, and the chemical formula is C4H4ClN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-chloropyrimidine with a minimum assay of 97%. This product is suitable for research and chemical synthesis applications and is not represented as USP, BP, or EP grade.
How should 2-Amino-5-chloropyrimidine be handled safely?
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2-Amino-5-chloropyrimidine is classified as dangerous. It is harmful if swallowed and causes serious eye damage. Appropriate personal protective equipment, including eyeshields, a face shield, gloves, and a dust mask (type N95 or equivalent), must be worn. Handle in a well-ventilated area.
Is 2-Amino-5-chloropyrimidine a controlled substance?
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The provided data does not indicate that 2-Amino-5-chloropyrimidine is a controlled substance.
How is 2-Amino-5-chloropyrimidine packed and exported?
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2-Amino-5-chloropyrimidine is UN 2811, Hazard Class 6.1, Packing Group III. Tech Serve Solutions adheres to all international regulations for packing and exporting hazardous chemicals.
How can I request a sample or quote for 2-Amino-5-chloropyrimidine?
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Please contact our sales team or use the online enquiry form on our website to request a sample or a quote for 2-Amino-5-chloropyrimidine.
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