2-Amino-5-ethyl-1,3,4-thiadiazole
2-Amino-5-ethyl-1,3,4-thiadiazole (CAS: 14068-53-2) is a heterocyclic organic compound with the molecular formula C4H7N3S and a molecular weight of 129.18 g/mol. This thiadiazole derivative is primarily utilised as a building block in chemical synthesis. It plays a crucial role in the development of novel heterocyclic compounds, including dyes and ligands, by participating in various coupling and derivatisation reactions.
- Synonyms
- 14068-53-2C4H7N3S

Synthesis of Indole Dyes
This compound serves as a precursor for the synthesis of hetarylazoindole dyes, a class of colorants with potential applications in various dyeing processes. It is also used in the specific synthesis of 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.
Ligand Synthesis
2-Amino-5-ethyl-1,3,4-thiadiazole is employed in the preparation of specialised ligands, such as N-(5-ethyl-[1,3,4]-thiadiazole-2-yl) toluenesulfonamide. These ligands can be valuable in coordination chemistry and catalysis research.
Heterocyclic Chemistry Building Block
As a versatile heterocyclic building block, it is instrumental in the construction of more complex organic molecules within medicinal chemistry and materials science research.
| Molecular weight | 129.18 |
|---|---|
| Empirical formula | C4H7N3S |
| Assay | 97% |
| Application | 2-Amino-5-ethyl-1,3,4-thiadiazole was used in the synthesis of:• 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole1• hetarylazoindole dyes2• N-(5-ethyl-[1,3,4]-thiadiazole-2-yl) toluenesulfonamide ligand3 |
| Melting point | 200-203 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-ethyl-1,3,4-thiadiazole used for?
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2-Amino-5-ethyl-1,3,4-thiadiazole is used as a building block in chemical synthesis, particularly for creating hetarylazoindole dyes and specific ligands. It is also a component in the synthesis of compounds like 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.
What are the CAS number and formula for 2-Amino-5-ethyl-1,3,4-thiadiazole?
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The CAS number for 2-Amino-5-ethyl-1,3,4-thiadiazole is 14068-53-2, and its empirical formula is C4H7N3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-ethyl-1,3,4-thiadiazole with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade, and it is intended for research and laboratory use.
How should 2-Amino-5-ethyl-1,3,4-thiadiazole be handled safely?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Amino-5-ethyl-1,3,4-thiadiazole, and can facilitate international shipments.
How can I request a sample or quote for 2-Amino-5-ethyl-1,3,4-thiadiazole?
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To request a sample or a quote for 2-Amino-5-ethyl-1,3,4-thiadiazole, please contact our sales department through the website or by phone, providing your specific requirements.
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