4-(1-Piperidinyl)benzaldehyde
4-(1-Piperidinyl)benzaldehyde (CAS: 10338-57-5), with the molecular formula C12H15NO and a molecular weight of 189.25 g/mol, is a valuable organic building block. This compound, characterised by its aldehyde and piperidine functionalities, serves as a key intermediate in the synthesis of diverse chemical entities. It is particularly useful in the development of anti-inflammatory agents, antibacterial compounds, and receptor antagonists.
- IUPAC
- 1-(4-Formylphenyl)piperidine
- Synonyms
- 1-(4-Formylphenyl)piperidine
Synthesis of Anti-inflammatory Agents
4-(1-Piperidinyl)benzaldehyde is utilized as a reactant in the preparation of novel anti-inflammatory compounds. Its structural features enable the incorporation into more complex molecules designed for therapeutic applications.
Development of Antibacterial Agents
This aldehyde is a precursor for synthesizing piperidine-incorporated α-aminophosphonates, which have shown potential as antibacterial agents. The compound facilitates the introduction of the piperidine moiety into target structures.
Creation of Growth Inhibitors
The compound serves as a building block for 5-hydroxyaurone derivatives. These derivatives have been investigated for their growth inhibitory effects against human umbilical vein endothelial cells (HUVEC) and certain cancer cell lines.
Preparation of NMDA Receptor Antagonists
4-(1-Piperidinyl)benzaldehyde is employed in the synthesis of NR2B selective NMDA receptor antagonists. These compounds are of interest in neurological research and potential therapeutic interventions.
Synthesis of Fulleropyrrolidines
This chemical is a useful intermediate for the synthesis of fulleropyrrolidines, a class of compounds with diverse applications in materials science and medicinal chemistry.
| Molecular weight | 189.25 |
|---|---|
| Empirical formula | C12H15NO |
| Assay | 97% |
| Application | Reactant for synthesis of:• Anti-inflammatory agents1• Piperidine incorporated α-aminophosphonates for antibacterial agents2• 5-Hydroxyaurone derivatives as growth inhibitors against HUVEC and some cancer cell lines3• NR2B selective NMDA receptor antagonists4• Fulleropyrrolidines5• Fluorophores for monitoring polymerization processes6 |
| Melting point | 61-64 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(1-Piperidinyl)benzaldehyde used for?
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4-(1-Piperidinyl)benzaldehyde is primarily used as a reactant and intermediate in the synthesis of various chemical compounds, including anti-inflammatory agents, antibacterial agents, growth inhibitors, NMDA receptor antagonists, and fulleropyrrolidines. It also finds application in the development of fluorophores for monitoring polymerization processes.
What are the CAS number and formula for 4-(1-Piperidinyl)benzaldehyde?
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The CAS number for 4-(1-Piperidinyl)benzaldehyde is 10338-57-5, and its molecular formula is C12H15NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(1-Piperidinyl)benzaldehyde with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product documentation. For specific grade requirements, please contact our sales team.
How should 4-(1-Piperidinyl)benzaldehyde be handled safely?
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Warning: 4-(1-Piperidinyl)benzaldehyde is a warning hazardous substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
How is 4-(1-Piperidinyl)benzaldehyde packaged and shipped?
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Tech Serve Solutions exports fine chemicals globally. Products are packaged according to international shipping regulations and customer requirements to ensure safe transit. Please contact us for specific packaging and shipping inquiries.
How can I request a sample or quote for 4-(1-Piperidinyl)benzaldehyde?
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To request a sample or a quote for 4-(1-Piperidinyl)benzaldehyde, please visit the product page on our website or contact our dedicated sales team directly. Provide your contact details and the quantity required.
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