4-(1-Pyrrolidinyl)piperidine
4-(1-Pyrrolidinyl)piperidine (CAS 5004-07-9), with the molecular formula C9H18N2 and a molecular weight of 154.25 g/mol, is a versatile heterocyclic building block. It is utilised as a reactant in the synthesis of diverse small molecules, including those designed as ligands for methyl-lysine binding proteins and selective inhibitors for Polo-like kinase 1. This compound plays a role in the development of therapeutics targeting various conditions.
- IUPAC
- 1-(Piperidin-4-yl)pyrrolidine
- Synonyms
- 1-(Piperidin-4-yl)pyrrolidine
Synthesis of Methyl-Lysine Binding Protein Ligands
This compound serves as a key reactant in the synthesis of small molecule ligands designed to interact with methyl-lysine binding proteins, contributing to research in epigenetics and related fields.
Development of Colorectal Carcinoma Therapeutics
It is employed in the creation of small molecules that have demonstrated the ability to restore E-cadherin expression and reduce cellular invasion in colorectal carcinoma models.
Preparation of Kinase Inhibitors
The chemical is a precursor for synthesizing selective Polo-like kinase 1 inhibitors, important in the research of cell cycle regulation and cancer therapeutics.
Research into Metabolic Regulation
It functions as a building block for molecules investigated for their effects on plasma glucose levels, contributing to research in metabolic disorders.
Synthesis of Receptor Antagonists
4-(1-Pyrrolidinyl)piperidine is used in the synthesis of vasopressin 1b receptor antagonists, valuable tools in pharmacological research.
Development of Anti-inflammatory Agents
This compound is a reactant in the preparation of IKKβ inhibitors, which are explored for their potential anti-inflammatory properties.
| Molecular weight | 154.25 |
|---|---|
| Empirical formula | C9H18N2 |
| Assay | 95% |
| Application | Reactant for synthesis of: Small molecule ligands of methyl-lysine binding proteins1 Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells2 Selective Polo-like kinase 1 inhibitors3 Molecules with effects on plasma glucose levels4 Vasopressin1b receptor antagonists5 IKKβ inhibitors6 |
| Melting point | 53-56 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(1-Pyrrolidinyl)piperidine used for?
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4-(1-Pyrrolidinyl)piperidine is used as a reactant in the synthesis of various small molecules, including ligands for methyl-lysine binding proteins, potential therapeutics for colorectal carcinoma, selective kinase inhibitors, and molecules affecting plasma glucose levels, among others.
What is the CAS number and formula for 4-(1-Pyrrolidinyl)piperidine?
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The CAS number is 5004-07-9, and the empirical formula is C9H18N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 95%. We do not represent it as USP, BP, EP or other pharmacopoeial grades.
How should 4-(1-Pyrrolidinyl)piperidine be handled?
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Handle with appropriate personal protective equipment: wear a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. This compound is classified as a warning substance and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for 4-(1-Pyrrolidinyl)piperidine?
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Please contact our sales team via our website or direct email to request a sample or obtain a quotation for 4-(1-Pyrrolidinyl)piperidine.
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