N-Boc-2-aminoacetaldehyde
N-Boc-2-aminoacetaldehyde (CAS 89711-08-0) is a protected amino aldehyde with the linear formula HCOCH2NHCO2C(CH3)3 and a molecular weight of 159.18 g/mol. This compound serves as a valuable building block in organic synthesis. It is particularly useful in the synthesis of pyrrolidines and in the α-methylenation of amino aldehydes, enabling efficient and novel molecular constructions for various chemical research applications.
- IUPAC
- tert-Butyl N-(2-oxoethyl)carbamate
- Synonyms
- tert-Butyl N-(2-oxoethyl)carbamate
Pyrrolidine Synthesis
This compound participates in a three-component synthesis of pyrrolidines through a 1,3-dipolar cycloaddition reaction, offering a route to diverse heterocyclic structures.
α-Methylenation Reactions
N-Boc-2-aminoacetaldehyde undergoes efficient α-methylenation using formaldehyde and specific catalysts, such as pyrrolidine proprionic acid or the dipeptide L-Pro-β-Ala, enabling the introduction of a methylene group.
Organic Building Block
As a protected amino aldehyde, it functions as a versatile intermediate in complex organic syntheses, facilitating the construction of various carbon backbones and functional groups.
| Molecular weight | 159.18 |
|---|---|
| Linear formula | HCOCH2NHCO2C(CH3)3 |
| Assay | 95% |
| Refractive index | n20/D 1.455(lit.) |
| Storage temperature | −20°C |
| Application | α-Methylenation of this amino aldehyde proceeds in a quick and efficient manner using a recently reported protocol involving formaldehyde and catalysis by either pyrrolidine proprionic acid or the dipeptide L-Pro-β-Ala.1Also used in a three-component synthesis of pyrrolidines involving 1,3-dipolar cycloaddition.2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CTSK(1513) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-2-aminoacetaldehyde used for?
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N-Boc-2-aminoacetaldehyde is primarily used as a building block in organic synthesis, particularly for the synthesis of pyrrolidines and in α-methylenation reactions.
What is the CAS number and formula for N-Boc-2-aminoacetaldehyde?
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The CAS number is 89711-08-0, and the linear formula is HCOCH2NHCO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-2-aminoacetaldehyde with an assay of 95%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety precautions for handling N-Boc-2-aminoacetaldehyde?
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Handling N-Boc-2-aminoacetaldehyde requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a flash point of 113 °C (235.4 °F) and a WGK rating of 3 in Germany.
How is N-Boc-2-aminoacetaldehyde stored and shipped?
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N-Boc-2-aminoacetaldehyde should be stored at -20°C. Tech Serve Solutions exports chemicals globally, adhering to all necessary shipping regulations.
How can I request a sample or quote for N-Boc-2-aminoacetaldehyde?
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To request a sample or a quote, please contact our sales department via the website or by phone, providing the product name and CAS number (89711-08-0).
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