N-Boc-1,6-hexanediamine
N-Boc-1,6-hexanediamine (CAS 51857-17-1) is an organic compound with the molecular formula C11H24N2O2 and a molecular weight of 216.32 g/mol. It serves as a valuable reagent for introducing a C6-spacer in chemical synthesis. Its structure, featuring a protected amine and a free amine, makes it useful in various chemical biology and organic building block applications, facilitating the construction of complex molecules.
- IUPAC
- N-Boc-1,6-diaminohexane,tert-Butyl-N-(6-aminohexyl)carbamate
- Synonyms
- tert-Butyl N-(6-aminohexyl)carbamateN-Boc-1,6-diaminohexane

Chemical Synthesis
Utilised as a key building block in organic synthesis, N-Boc-1,6-hexanediamine allows for the controlled introduction of a six-carbon aliphatic spacer. The Boc protecting group enables selective reactions at the free amine functionality.
Bifunctional Linkers
This compound functions as a bifunctional linker, enabling the connection of two different molecular entities. The protected amine can be deprotected and reacted later, offering versatility in conjugation strategies.
Chemical Biology
In chemical biology, N-Boc-1,6-hexanediamine is employed to modify biomolecules or create probes. Its hexanediamine backbone provides a flexible linker for attaching labels, drugs, or other functional groups.
| Molecular weight | 216.32 |
|---|---|
| Empirical formula | C11H24N2O2 |
| Assay | ≥98.0% (GC) |
| Density | 0.965 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.462 |
| Application | Reagent for the introduction of a C6-spacer. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 125 °C / 257 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-1,6-hexanediamine used for?
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N-Boc-1,6-hexanediamine is primarily used as a reagent for introducing a C6-spacer in chemical synthesis, acting as a valuable building block and bifunctional linker in organic and chemical biology applications.
What are the CAS number and molecular formula for N-Boc-1,6-hexanediamine?
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The CAS number for N-Boc-1,6-hexanediamine is 51857-17-1, and its empirical formula (Hill notation) is C11H24N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-1,6-hexanediamine with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should N-Boc-1,6-hexanediamine be handled safely?
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N-Boc-1,6-hexanediamine is classified as Danger (GHS05) with hazard statement H314, indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment, including faceshields, goggles, gloves, and a suitable respirator, must be used. Handle in a well-ventilated area and seek immediate medical attention if exposed.
Is N-Boc-1,6-hexanediamine exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including N-Boc-1,6-hexanediamine, serving customers worldwide.
How can I request a quote or sample for N-Boc-1,6-hexanediamine?
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To request a quote or sample for N-Boc-1,6-hexanediamine, please contact our sales team through the website or by phone, providing your specific requirements.
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