N-Boc-1,4-butanediamine
N-Boc-1,4-butanediamine (CAS 68076-36-8) is a protected diamine with a molecular weight of 188.27 g/mol. This compound features a tert-butoxycarbonyl (Boc) protecting group on one amine, rendering it selectively reactive. It serves as a valuable building block in organic synthesis, particularly for creating bifunctional molecules and linkers used in chemical biology and crosslinking applications.
- IUPAC
- N-Boc-1,4-diaminobutane,tert-Butyl N-(4-aminobutyl)carbamate
- Synonyms
- (CH3)3COCONH(CH2)4NH2N-Boc-1,4-diaminobutanetert-Butyl N-(4-aminobutyl)carbamate
Organic Synthesis Building Block
N-Boc-1,4-butanediamine is utilised as a versatile intermediate in the synthesis of more complex organic molecules. The Boc protecting group allows for controlled reactions at the free amine, enabling stepwise functionalization.
Bifunctional Linker Synthesis
This compound is instrumental in constructing bifunctional linkers, which are crucial for conjugating different molecular entities in areas like drug discovery and materials science.
Chemical Biology Applications
It finds application in chemical biology for creating probes or modified biomolecules, facilitating studies into biological processes and interactions.
Peptide and Polymer Chemistry
N-Boc-1,4-butanediamine can be incorporated into peptide synthesis or polymer structures, introducing specific functionalities or modifying material properties.
| Molecular weight | 188.27 |
|---|---|
| Linear formula | (CH3)3COCONH(CH2)4NH2 |
| Assay | ≥97.0% (GC/NT) |
| Density | 0.984 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.460 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Transport (UN / ADR) | UN 2735PSN2 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-1,4-butanediamine used for?
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N-Boc-1,4-butanediamine is primarily used as a building block in organic synthesis, for creating bifunctional linkers, in chemical biology, and in peptide and polymer chemistry.
What is the CAS number and formula for N-Boc-1,4-butanediamine?
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The CAS number is 68076-36-8. The linear formula is (CH3)3COCONH(CH2)4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-1,4-butanediamine with an assay of ≥97.0% (GC/NT). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should N-Boc-1,4-butanediamine be handled safely?
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N-Boc-1,4-butanediamine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, and face shields, is essential. Handle in a well-ventilated area and avoid contact.
Is N-Boc-1,4-butanediamine a controlled substance?
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The provided data does not indicate that N-Boc-1,4-butanediamine is a controlled substance.
How is N-Boc-1,4-butanediamine packed and shipped?
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This chemical is shipped according to transport regulations (UN 2735, PSN2 8 / PGIII). Specific packaging details are available upon request.
How can I request a sample or quote for N-Boc-1,4-butanediamine?
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Please use the 'Request a Quote' or 'Contact Us' form on our website to inquire about samples or obtain a quotation.
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