2-Amino-5-fluorobenzoic acid
2-Amino-5-fluorobenzoic acid (CAS: 446-08-2, H2NC6H3(F)CO2H) is a fluorinated aromatic amino acid derivative with a molecular weight of 155.13 g/mol. It is primarily utilised as a building block in chemical synthesis. Notably, it serves as a key intermediate in the creation of styrylquinazolinones, a class of compounds investigated for their potential anticancer properties. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- 5-Fluoroanthranilic acid
- Synonyms
- 5-Fluoroanthranilic acid
Synthesis of Anticancer Agents
2-Amino-5-fluorobenzoic acid is employed in the synthesis of styrylquinazolinones. These compounds are under investigation for their potential as anticancer agents, highlighting the role of this chemical in pharmaceutical research and development.
Chemical Synthesis Intermediate
As a functionalised aromatic molecule, it serves as a versatile intermediate in various organic synthesis pathways. Its specific structure allows for further chemical modifications to create more complex molecules for diverse applications.
Research and Development
This compound is valuable in chemical biology and peptide chemistry research, particularly in the synthesis of unnatural amino acid derivatives. It aids in exploring novel molecular structures and their biological activities.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | H2NC6H3(F)CO2H |
| Assay | 97% |
| Application | Used in the synthesis of styrylquinazolinones which are potential anticancer agents.1 |
| Melting point | 181-183 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-fluorobenzoic acid used for?
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2-Amino-5-fluorobenzoic acid is used in the synthesis of styrylquinazolinones, which are investigated as potential anticancer agents, and as a general intermediate in chemical synthesis and research.
What is the CAS number and chemical formula for 2-Amino-5-fluorobenzoic acid?
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The CAS number is 446-08-2, and the chemical formula is H2NC6H3(F)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-fluorobenzoic acid with an assay of 97%. This is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should 2-Amino-5-fluorobenzoic acid be handled?
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Handle with appropriate personal protective equipment including a dust mask (NIOSH N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
How is 2-Amino-5-fluorobenzoic acid shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details for 2-Amino-5-fluorobenzoic acid can be provided upon request.
How can I request a sample or quote for 2-Amino-5-fluorobenzoic acid?
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To request a sample or a quotation for 2-Amino-5-fluorobenzoic acid, please contact our sales team directly through the website or by phone.
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