2-(Di-tert-butylphosphino)-1-(2-methoxyphenyl)-1H-pyrrole
2-(Di-tert-butylphosphino)-1-(2-methoxyphenyl)-1H-pyrrole (CAS: 1053658-91-5) is a complex organophosphorus compound with the molecular formula C19H28NOP and a molecular weight of 317.41 g/mol. This specialized phosphine ligand is primarily employed in advanced organic synthesis, particularly in catalysing cross-coupling reactions. Its unique structure offers valuable properties for chemists developing new synthetic routes and complex molecules.
- IUPAC
- cataCXium® POMetB
Buchwald-Hartwig Amination
This compound functions as a highly effective ligand in palladium-catalysed Buchwald-Hartwig amination reactions, facilitating the formation of carbon-nitrogen bonds.
Cross-Coupling Reactions
It serves as a key component in various palladium-catalysed cross-coupling reactions, enabling efficient bond formation in complex organic synthesis.
Catalysis
As a phosphine ligand, it is instrumental in homogeneous catalysis, enhancing the reactivity and selectivity of transition metal catalysts in diverse organic transformations.
| Molecular weight | 317.41 |
|---|---|
| Empirical formula | C19H28NOP |
| Assay | 95% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | Buchwald-Hartwig Cross Coupling Reaction |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Di-tert-butylphosphino)-1-(2-methoxyphenyl)-1H-pyrrole primarily used for?
+
This compound is primarily used as a phosphine ligand in various catalysed organic synthesis reactions, notably in Buchwald-Hartwig cross-coupling reactions.
What are the CAS number and chemical formula for this compound?
+
The CAS number is 1053658-91-5 and the chemical formula is C19H28NOP.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product at an assay of 95%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling this chemical?
+
When handling, it is essential to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a WGK Germany rating of 3.
Can Tech Serve Solutions export this chemical internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
+
Please contact our sales team via the website or direct email to request a quotation or to arrange for a sample.
▶ Related products
Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis