2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole
2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole (CAS: 794527-14-3) is a phosphine ligand with a molecular weight of 382.52 g/mol. It is recognised for its efficacy as a catalyst in coupling reactions, particularly with challenging aryl chlorides. This compound is a valuable tool in modern synthetic chemistry, facilitating complex bond formations with high efficiency.
- IUPAC
- 2-(Dicyclohexylphosphino)-1-mesityl-1H-imidazole,cataCXium® PICy
- Synonyms
- 794527-14-3C24H35N2P2-(Dicyclohexylphosphino)-1-mesityl-1H-imidazolecataCXium® PICy

Catalysis in Coupling Reactions
This phosphine ligand serves as an effective catalyst in various cross-coupling reactions. It exhibits particular utility in the catalytic coupling of aryl chlorides, which are often less reactive substrates than their bromide or iodide counterparts.
Asymmetric Synthesis
As a chiral catalyst component, it is instrumental in asymmetric synthesis, enabling the formation of enantiomerically enriched products. Its structure allows for precise control over stereochemical outcomes in catalysed transformations.
Organic Synthesis
The compound is a versatile reagent in general organic synthesis, facilitating the construction of complex molecular architectures. Its phosphine nature makes it adept at coordinating with transition metals, forming active catalytic species.
| Molecular weight | 382.52 |
|---|---|
| Empirical formula | C24H35N2P |
| Assay | 95% |
| Application | Catalyst for coupling reactions of aryl chlorides1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole used for?
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This compound is primarily used as a catalyst, particularly in coupling reactions involving aryl chlorides, and in asymmetric synthesis.
What is the CAS number and molecular formula for this compound?
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The CAS number is 794527-14-3, and its empirical formula is C24H35N2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 95%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
What are the safety and handling recommendations?
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When handling, it is essential to use Eyeshields and Gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. This compound is classified under WGK 2 (Germany).
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and handling for international shipment.
How can I request a sample or quote?
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Please contact our sales team directly via our website or by phone to request a sample or obtain a quotation for 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole.
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