2-(Dicyclohexylphosphino)-1-phenylindole
2-(Dicyclohexylphosphino)-1-phenylindole (CAS 740815-36-5) is a phosphine compound with the empirical formula C26H32NP and a molecular weight of 389.51 g/mol. It serves as a valuable ligand and catalyst in various organic synthesis applications, particularly in stereoselective reactions and cross-coupling processes. This compound is widely utilised in academic research and industrial settings for the development of new chemical entities and efficient synthetic methodologies.
- IUPAC
- cataCXium® PInCy
Stereoselective Isomerisation
This compound functions as a catalyst for the stereoselective isomerisation of terminal alkenes, enabling precise control over stereochemistry in organic transformations.
Reductive Carbonylation
It is employed as a catalyst in the reductive carbonylation of aryl and vinyl halides, a crucial process for the synthesis of carbonyl-containing compounds.
Cross-Coupling Reactions
2-(Dicyclohexylphosphino)-1-phenylindole is a key ligand in various palladium-catalyzed cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.
Heck Reaction
The compound acts as a catalyst in the Heck reaction, a fundamental method for coupling alkenes with aryl or vinyl halides.
Buchwald-Hartwig Amination
It is utilised as a ligand in Buchwald-Hartwig amination reactions, enabling the formation of C-N bonds through the coupling of amines with aryl or heteroaryl halides.
| Molecular weight | 389.51 |
|---|---|
| Empirical formula | C26H32NP |
| Assay | 95% (NMR) |
| Application | Catalyst for:• Stereoselective isomerization of terminal alkenes1• Reductive carbonylation of aryl and vinyl halides2• Heck reaction3• Cross-coupling reactions4• Buchwald-Hartwig amination5• Ligand for palladium-catalyzed amination of aryl and heteroaryl chlorides6 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Dicyclohexylphosphino)-1-phenylindole used for?
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2-(Dicyclohexylphosphino)-1-phenylindole is used as a catalyst and ligand in various organic synthesis applications, including stereoselective isomerisation of alkenes, reductive carbonylation, Heck reactions, and cross-coupling reactions such as Buchwald-Hartwig amination.
What are the CAS number and formula for 2-(Dicyclohexylphosphino)-1-phenylindole?
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The CAS number is 740815-36-5 and the empirical formula is C26H32NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a purity of 95% (NMR). This is a research-grade chemical and TSS does not represent it as USP, BP, EP, or any pharmacopoeial grade.
What are the safety considerations when handling 2-(Dicyclohexylphosphino)-1-phenylindole?
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Safety precautions include wearing eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK Germany classification of 3, indicating it is hazardous to water.
How is 2-(Dicyclohexylphosphino)-1-phenylindole shipped?
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Tech Serve Solutions exports and ships chemicals globally, adhering to all necessary regulations for safe and compliant transport.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone.
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