2-(Di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole

CAS 672937-61-0C18H26NPCatalysis & Inorganic

2-(Di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole (CAS: 672937-61-0), with the molecular formula C18H26NP and a molecular weight of 287.38 g/mol, is a sophisticated phosphine ligand. It is recognised for its utility in various cross-coupling reactions and catalytic processes. This compound is a key component in advancing complex organic synthesis, particularly within the fields of catalysis and chiral chemistry, offering precise control in molecular transformations.

IUPAC: N-Phenyl-2-(di-tert-butylphosphino)pyrrole,N-Phenylpyrrol-2-yldi-tert-butylphosphine,cataCXium® PtB,phosphine ligands

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2-(Di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole (C18H26NP) — chemical structure, CAS 672937-61-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsPhosphine CompoundscataCXium Catalysts More...

01 /Applications

Buchwald-Hartwig Cross Coupling

This phosphine ligand is effectively employed in palladium-catalysed Buchwald-Hartwig amination reactions, facilitating the formation of carbon-nitrogen bonds. It enables efficient coupling between aryl halides or pseudohalides and amines.

Suzuki-Miyaura Coupling

Utilised as a ligand in Suzuki-Miyaura cross-coupling reactions, it promotes the formation of carbon-carbon bonds by coupling organoboron compounds with organic halides or pseudohalides. This is crucial for synthesising biaryl compounds and other complex organic molecules.

Dehydrogenation Catalysis

This compound serves as a ligand in catalytic systems for dehydrogenation processes. It can facilitate the removal of hydrogen from organic molecules, which is important in various synthetic transformations and energy-related research.

02 /Properties

Molecular weight	287.38
Empirical formula	C18H26NP
Assay	95%

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

672937-61-0

Beilstein registry

9626114

05 /Additional specifications

Ligand For	Buchwald-Hartwig Cross Coupling ReactionDehydrogenationSuzuki-Miyaura Coupling

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2-(Di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole used for?

This compound is primarily used as a phosphine ligand in catalytic cross-coupling reactions such as Buchwald-Hartwig amination and Suzuki-Miyaura coupling, as well as in dehydrogenation processes. It is instrumental in asymmetric synthesis and general chemical synthesis.

What is the CAS number and molecular formula for this compound?

The CAS number is 672937-61-0 and the molecular formula is C18H26NP.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of 95%. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard to water.

How is this chemical packed, shipped, and exported?

Tech Serve Solutions professionally packs, ships, and exports fine chemicals globally, adhering to all necessary regulations to ensure safe and timely delivery to your laboratory or facility.

How can I request a sample or quote?

To request a sample or a quote for 2-(Di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole, please use the contact form on our website or reach out to our sales team directly.