5-Benzyloxyindole-3-carboxaldehyde
5-Benzyloxyindole-3-carboxaldehyde (CAS: 6953-22-6), with the molecular formula C16H13NO2 and a molecular weight of 251.28, is a fine chemical supplied by Tech Serve Solutions. This yellow to brown powder is primarily used as a reactant and building block in organic synthesis. It serves as a key intermediate in the preparation of various complex molecules, including potential pharmaceutical agents and specialised dyes, underscoring its utility in advanced chemical research and development.
- IUPAC
- 5-Benzyloxy-3-formylindole,NSC 71049

Synthesis of Indole Derivatives
Serves as a crucial intermediate for synthesising a wide range of indole-based compounds. These derivatives are explored for their potential pharmacological activities, including applications as topoisomerase II inhibitors and selective serotonin receptor agonists.
Preparation of Heterocyclic Compounds
Utilised in the construction of complex heterocyclic structures, such as benzimidazoles. These compounds are investigated for their potential as antibacterial agents, contributing to the development of new antimicrobial therapies.
Dye Synthesis
Acts as a precursor in the synthesis of merocyanine dyes. These specialized dyes find applications in various fields, including photodynamic therapy and materials science.
Pharmaceutical Intermediate
A valuable building block in medicinal chemistry for creating novel drug candidates. It is employed in the development of compounds targeting various biological pathways, such as PI3 kinase and VEGF, for potential therapeutic use.
| Molecular weight | 251.28 |
|---|---|
| Empirical formula | C16H13NO2 |
| Form | powder |
| Colour | yellow to brown |
| Storage temperature | 2-8°C |
| Application | Reactant for preparation of:• Rhodanine merocyanine dyes1• Potential topoisomerase II inhibitors2• Azithromycin derivatives3• Inhibitors of PI3 kinase-α and the mammalian target of rapamycin4• Cytotoxic agents5• Vascular endothelial growth factor (VEGF) inhibitor6• Derivatives of vancomycin and eremomycin7• Benzimidazoles as potential antibacterial agents8• Light-dependent tumor necrosis factor-α antagonists9• Serotonin 5-HT4 Receptor agonists10 |

Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Benzyloxyindole-3-carboxaldehyde used for?
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5-Benzyloxyindole-3-carboxaldehyde (CAS: 6953-22-6) is used as a reactant and building block in organic synthesis for preparing various complex molecules, including dyes, potential pharmaceutical agents, and heterocyclic compounds.
What are the CAS number and molecular formula of 5-Benzyloxyindole-3-carboxaldehyde?
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The CAS number is 6953-22-6, and the molecular formula is C16H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a technical/research grade. We do not represent it as USP, BP, or EP grade.
How should 5-Benzyloxyindole-3-carboxaldehyde be handled?
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This compound is a warning substance. It can cause skin irritation and serious eye irritation (H317, H319). Ensure adequate ventilation, wear appropriate personal protective equipment including gloves, eyeshields, and a face shield, and use a dust mask type N95 (US). Avoid contact with skin and eyes.
Is 5-Benzyloxyindole-3-carboxaldehyde shipped or exported by TSS?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 5-Benzyloxyindole-3-carboxaldehyde.
How can I request a sample or quote?
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To request a sample or obtain a quote for 5-Benzyloxyindole-3-carboxaldehyde, please contact our sales team through the website or by phone.
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