2-Methoxy-1,4-naphthoquinone
2-Methoxy-1,4-naphthoquinone (CAS 2348-82-5), with the molecular formula C11H8O3 and a molecular weight of 188.18 g/mol, is a naphthoquinone derivative. It serves as a valuable building block in organic synthesis, particularly in the preparation of functionalised naphthoquinone derivatives. This compound is widely utilised in chemical research and development for creating novel molecular structures.
- Synonyms
- 2-Methoxy-1,4-naphthoquinone1,4-Naphthalenedione, 2-methoxy-

Synthesis of Substituted Naphthoquinones
2-Methoxy-1,4-naphthoquinone is employed as a precursor for synthesising various 2-amino-1,4-naphthoquinone derivatives. These derivatives have been prepared with diverse substituents on the phenyl ring, enabling exploration of structure-activity relationships.
Organic Building Block
As a carbonyl compound and ketone, it functions as a versatile building block in organic synthesis. Its naphthoquinone core allows for further functionalisation and incorporation into more complex molecular architectures.
Chemical Research and Development
This compound is utilised in laboratory settings for research purposes, contributing to the advancement of synthetic organic chemistry and the discovery of new chemical entities.
| Molecular weight | 188.18 |
|---|---|
| Empirical formula | C11H8O3 |
| Assay | 98% |
| Application | 2-Methoxy-1,4-naphthoquinone was used in the preparation of 2-(4-X-phenylene)amine-1,4-naphthoquinones (X= ferrocenyl, OMe, Me, I, Cl and NO2)1. |
| Melting point | 184-187 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-1,4-naphthoquinone used for?
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2-Methoxy-1,4-naphthoquinone is primarily used as a building block in organic synthesis, notably for preparing 2-(4-X-phenylene)amine-1,4-naphthoquinones and other functionalised naphthoquinone derivatives.
What are the CAS number and molecular formula for 2-Methoxy-1,4-naphthoquinone?
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The CAS number for 2-Methoxy-1,4-naphthoquinone is 2348-82-5, and its molecular formula is C11H8O3.
What grade and purity does Tech Serve Solutions supply for 2-Methoxy-1,4-naphthoquinone?
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Tech Serve Solutions supplies 2-Methoxy-1,4-naphthoquinone with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Methoxy-1,4-naphthoquinone be handled safely?
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Handle 2-Methoxy-1,4-naphthoquinone with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation. It is classified as a Warning substance, causing skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
Is 2-Methoxy-1,4-naphthoquinone exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Methoxy-1,4-naphthoquinone.
How can I request a quote or sample for 2-Methoxy-1,4-naphthoquinone?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (2348-82-5).
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