2-Mesitylenesulfonyl chloride
2-Mesitylenesulfonyl chloride (CAS 773-64-8) is a key organic building block with the linear formula (CH3)3C6H2SO2Cl and a molecular weight of 218.70 g/mol. This compound, also known as 2,4,6-Trimethylbenzenesulfonyl chloride, is primarily utilised in chemical synthesis. Its reactive sulfonyl chloride group makes it a valuable reagent for introducing the mesitylenesulfonyl moiety in various organic transformations, contributing to the development of complex molecules.
- IUPAC
- 2,4,6-Trimethylbenzenesulfonyl chloride
- Synonyms
- 2,4,6-Trimethylbenzenesulfonyl chloride

Organic Synthesis Intermediate
Serves as a crucial intermediate in the synthesis of diverse organic compounds. It is employed to introduce the 2,4,6-trimethylbenzenesulfonyl group, facilitating the construction of more complex molecular architectures.
Reagent for Sulfonylation
Utilised as a sulfonating agent in organic chemistry. The sulfonyl chloride functionality readily reacts with nucleophiles, enabling the formation of sulfonamides, sulfonates, and related derivatives.
Building Block for Speciality Chemicals
Functions as a versatile building block in the development of speciality chemicals. Its unique structure and reactivity profile are leveraged in research and development settings for novel compound synthesis.
| Molecular weight | 218.70 |
|---|---|
| Linear formula | (CH3)3C6H2SO2Cl |
| Assay | 99% |
| Melting point | 55-57 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Mesitylenesulfonyl chloride used for?
+
2-Mesitylenesulfonyl chloride (CAS 773-64-8) is primarily used as an intermediate in organic synthesis and as a reagent for introducing the 2,4,6-trimethylbenzenesulfonyl group into other molecules.
What is the CAS number and chemical formula for 2-Mesitylenesulfonyl chloride?
+
The CAS number for 2-Mesitylenesulfonyl chloride is 773-64-8, and its linear formula is (CH3)3C6H2SO2Cl.
What grade and purity does Tech Serve Solutions supply for 2-Mesitylenesulfonyl chloride?
+
Tech Serve Solutions supplies 2-Mesitylenesulfonyl chloride with an assay of 99%. This product is not represented as USP, BP, or EP grade.
How should 2-Mesitylenesulfonyl chloride be handled?
+
2-Mesitylenesulfonyl chloride is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be used. Handle in a well-ventilated area.
Is 2-Mesitylenesulfonyl chloride available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Mesitylenesulfonyl chloride, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2-Mesitylenesulfonyl chloride?
+
To request a sample or a quotation for 2-Mesitylenesulfonyl chloride, please contact our sales department through the website or by phone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis