2-Mesitylmagnesium bromide solution
2-Mesitylmagnesium bromide solution (CAS: 2633-66-1) is an organometallic compound with the linear formula (CH3)3C6H2MgBr and a molecular weight of 223.39 g/mol. Supplied as a 1.0 M solution in diethyl ether, it is a key Grignard reagent. This arylmagnesium halide serves as a versatile building block in organic synthesis for introducing the mesityl group into various molecules, particularly in the preparation of complex organic compounds and pharmaceuticals.
- IUPAC
- 2,4,6-Trimethylphenylmagnesium bromide
Aryl Group Introduction
This Grignard reagent is instrumental in introducing the bulky 2,4,6-trimethylphenyl (mesityl) group into organic molecules. It participates in nucleophilic addition and substitution reactions to form new carbon-carbon bonds.
Synthesis of Complex Organic Molecules
Used as a precursor in multi-step syntheses, it enables the construction of intricate molecular architectures. Its reactivity is valuable in research and development settings for novel compound discovery.
Pharmaceutical Intermediate Preparation
The mesityl moiety can be a structural component in certain active pharmaceutical ingredients (APIs). This reagent facilitates the efficient synthesis of these critical intermediates.
Organometallic Chemistry Research
As a defined organometallic species, it is employed in academic and industrial research to explore reaction mechanisms and develop new synthetic methodologies.
| Molecular weight | 223.39 |
|---|---|
| Linear formula | (CH3)3C6H2MgBr |
| Density | 0.897 g/mL at 25 °C |
| Concentration | 1.0 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Mesitylmagnesium bromide solution used for?
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2-Mesitylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis for introducing the mesityl group into molecules, serving as a building block for complex organic compounds and pharmaceutical intermediates.
What is the CAS number and formula for 2-Mesitylmagnesium bromide solution?
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The CAS number is 2633-66-1 and the linear formula is (CH3)3C6H2MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Mesitylmagnesium bromide solution as a 1.0 M solution in diethyl ether. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this product?
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This solution is flammable (H225) and reacts violently with water, posing significant risks. It is corrosive (H314) and may cause respiratory irritation (H335), with potential carcinogenic effects (H351). It may also form explosive peroxides. Strict adherence to safety protocols, including handling under inert atmosphere and avoiding contact with water and ignition sources, is essential.
Is 2-Mesitylmagnesium bromide solution packed and shipped internationally?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like 2-Mesitylmagnesium bromide solution, adhering to all international shipping regulations.
How can I request a sample or a quote for 2-Mesitylmagnesium bromide solution?
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To request a sample or a quote, please contact our sales team via the website or directly via email, providing your specific requirements and delivery details.
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