Picropodophyllotoxin
Picropodophyllotoxin (CAS: 477-47-4, C22H22O8, MW: 414.41) is a complex organic compound supplied by Tech Serve Solutions. This white powder, assayed at ≥96% by HPLC, is recognised for its biological activity. It is primarily utilized in research settings for its potential roles in cell biology and signalling pathways, including those involving receptor tyrosine kinases. Its specific applications are often explored within advanced biochemical and pharmacological investigations.
- IUPAC
- (5R,5aS,8aR,9R)-9-Hydroxy-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,NSC 36407,PPP,Picropodophyllin

Biochemical Research
Picropodophyllotoxin serves as a valuable tool in biochemical research, particularly for studying cellular processes and molecular signalling pathways. Its known interactions make it useful for investigating receptor tyrosine kinase biology.
Cell Biology Studies
This compound is employed in cell biology to understand complex cellular functions. It can be used to probe mechanisms related to cell growth, differentiation, and response to various stimuli.
Pharmacological Investigations
Researchers may utilise Picropodophyllotoxin in pharmacological studies to explore potential therapeutic targets or mechanisms of action. Its role in kinase/phosphatase biology is of particular interest.
| Molecular weight | 414.41 |
|---|---|
| Empirical formula | C22H22O8 |
| Assay | ≥96% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >5 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 21-25-36/37/38-68 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Picropodophyllotoxin used for?
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Picropodophyllotoxin is primarily used in biochemical research, cell biology studies, and pharmacological investigations, particularly concerning receptor tyrosine kinase biology and cell signalling pathways.
What are the CAS number and formula for Picropodophyllotoxin?
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The CAS number for Picropodophyllotoxin is 477-47-4, and its molecular formula is C22H22O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Picropodophyllotoxin with a purity of ≥96% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Picropodophyllotoxin be handled safely?
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Picropodophyllotoxin is a Danger substance (GHS06) that is toxic if swallowed, harmful if inhaled or in contact with skin, and causes skin and eye irritation. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Handle in a well-ventilated area and avoid dust formation.
Is Picropodophyllotoxin a controlled substance?
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The provided data does not indicate that Picropodophyllotoxin is a controlled substance under standard regulations. Please consult local regulations for specific requirements.
How is Picropodophyllotoxin packed and shipped?
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Picropodophyllotoxin is typically supplied as a white powder and stored at 2-8°C. As a specialist global supplier and exporter, Tech Serve Solutions adheres to all regulations for packing and shipping hazardous materials internationally.
How can I request a quote or sample for Picropodophyllotoxin?
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To request a quote or sample for Picropodophyllotoxin, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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