Pifithrin-μ
Pifithrin-μ (CAS: 64984-31-2), a potent inhibitor of p53-dependent apoptosis, is a small molecule with the chemical formula C8H7NO2S and a molecular weight of 181.21 g/mol. It plays a critical role in cellular research, specifically in understanding apoptosis pathways and cell cycle regulation. Supplied by Tech Serve Solutions, this compound is primarily utilized in biological and biochemical research settings for its specific inhibitory properties.
- IUPAC
- 2-Phenylethynesulfonamide,PFTμ
- Synonyms
- 2-Phenylethynesulfonamide,PFTμ
Apoptosis Research
Pifithrin-μ is widely employed as a tool to investigate the mechanisms of apoptosis, particularly the p53-mediated pathway. Its ability to inhibit apoptosis allows researchers to study cellular survival and death processes in various biological contexts.
Cell Cycle Regulation Studies
This compound is valuable for research into cell cycle progression and checkpoints. By modulating apoptosis, Pifithrin-μ aids in the exploration of how cells control their division and respond to stress or damage.
Stem Cell Biology Research
As an inhibitor relevant to cell fate, Pifithrin-μ finds application in stem cell research, particularly in understanding differentiation and survival mechanisms. It can be used to modulate apoptosis in stem cell populations and their derivatives.
Biochemical and Signaling Pathway Analysis
Pifithrin-μ serves as a probe for analysing complex cellular signaling pathways. Its specificity in inhibiting p53-dependent apoptosis makes it useful for dissecting molecular interactions and cellular responses in neuroscience and other fields.
| Molecular weight | 181.21 |
|---|---|
| Empirical formula | C8H7NO2S |
| Assay | ≥97% (HPLC) |
| Form | solid |
| Solubility | DMSO: >10 mg/mLH2O: <2 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pifithrin-μ used for?
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Pifithrin-μ is primarily used in research as a specific inhibitor of p53-dependent apoptosis, aiding in the study of cell death pathways, cell cycle regulation, and related biological processes.
What are the CAS number and chemical formula for Pifithrin-μ?
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The CAS number for Pifithrin-μ is 64984-31-2, and its chemical formula is C8H7NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pifithrin-μ with a purity of ≥97% (HPLC). This is a research-grade chemical and is not intended for USP, BP, EP, pharmaceutical, nutraceutical, or food applications.
How should Pifithrin-μ be handled and stored?
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Pifithrin-μ is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302, H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Store desiccated at 2-8°C.
Is Pifithrin-μ a controlled substance?
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The provided safety data does not indicate that Pifithrin-μ is a controlled substance.
How is Pifithrin-μ shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting Pifithrin-μ worldwide, adhering to all relevant regulations.
How can I request a sample or quote for Pifithrin-μ?
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To request a sample or obtain a quote for Pifithrin-μ, please contact our sales department through the website or by phone.
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