GYKI 52466 hydrochloride
GYKI 52466 hydrochloride (CAS: 192065-56-8; C17H15N3O2 · HCl) is a yellow crystalline solid with a molecular weight of 329.78 g/mol. This compound functions as an AMPA/Kainate receptor antagonist, finding utility in neurological research. It is employed to investigate excitatory amino acid neurotransmission and related cellular signaling pathways. Supplied by Tech Serve Solutions, it is suitable for laboratory research applications.
- IUPAC
- 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
Neuroscience Research Tool
GYKI 52466 hydrochloride serves as a valuable research chemical for studying the function of AMPA and Kainate receptors, which are key components of excitatory neurotransmission in the central nervous system.
Investigating Glutamatergic Pathways
This compound aids in elucidating the role of ionotropic glutamate receptors in various physiological and pathological processes, contributing to a deeper understanding of neuronal function and dysfunction.
Cell Signaling Studies
Utilized in cell biology to probe signaling cascades mediated by excitatory amino acids, offering insights into cellular responses to neurotransmitter activity.
| Molecular weight | 329.78 |
|---|---|
| Empirical formula | C17H15N3O2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: soluble0.39 mg/mLethanol: soluble0.4 mg/mL0.1 M HCl: soluble0.68 mg/mLmethanol: soluble1 mg/mLH2O: >10 mg/mL |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GYKI 52466 hydrochloride used for?
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GYKI 52466 hydrochloride is primarily used as a research tool in neuroscience and cell biology to study AMPA/Kainate receptors and excitatory amino acid neurotransmission.
What is the CAS number and formula for GYKI 52466 hydrochloride?
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The CAS number for GYKI 52466 hydrochloride is 192065-56-8, and its formula is C17H15N3O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GYKI 52466 hydrochloride with a minimum purity of 98% as determined by HPLC. This product is intended for research purposes and is not supplied as USP, BP, or EP grade.
What are the safety precautions for handling GYKI 52466 hydrochloride?
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GYKI 52466 hydrochloride is classified as a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is GYKI 52466 hydrochloride shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. GYKI 52466 hydrochloride is carefully packed to ensure safe transit and can be exported worldwide.
How can I request a sample or quote for GYKI 52466 hydrochloride?
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To request a sample or obtain a quotation for GYKI 52466 hydrochloride, please contact our sales department through the website or by phone.
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