GW843682X
GW843682X (CAS: 660868-91-7, C22H18F3N3O4S) is a fine chemical with a molecular weight of 477.46 g/mol. Supplied as an off-white solid, this compound has demonstrated utility in biological research, particularly within cell biology and neuroscience studies. It is recognised as a potent inhibitor of Polo-like Kinases (PLKs), making it a valuable tool for investigating cell cycle regulation and related signalling pathways in academic and pharmaceutical research settings.
- IUPAC
- 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide,GW843682
Kinase Inhibition Research
GW843682X acts as an inhibitor for Polo-like Kinases (PLKs), which are crucial regulators of cell division. This property makes it a valuable research chemical for studying cell cycle progression and its aberrations.
Cell Biology Studies
As a bioactive small molecule, GW843682X is employed in cell biology research to probe fundamental cellular processes, including mitosis and DNA damage response, due to its specific interaction with serine/threonine kinases.
Neuroscience Research Tool
This compound is utilised within neuroscience research to investigate the roles of PLKs and related signalling pathways in neuronal function and development, contributing to a deeper understanding of neurological processes.
| Molecular weight | 477.46 |
|---|---|
| Empirical formula | C22H18F3N3O4S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GW843682X used for?
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GW843682X is primarily used as a research chemical for studying cell cycle regulation, kinase inhibition, and cellular signalling pathways, particularly within cell biology, neuroscience, and approved therapeutics research.
What is the CAS number and chemical formula for GW843682X?
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The CAS number for GW843682X is 660868-91-7, and its empirical formula is C22H18F3N3O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GW843682X with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should GW843682X be handled and stored?
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GW843682X is a Warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C.
Is GW843682X available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including GW843682X, to research institutions and companies worldwide.
How can I request a sample or quote for GW843682X?
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To request a sample or a quotation for GW843682X, please contact our sales department through the provided contact channels on the Tech Serve Solutions website.
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