2,4-Difluorothiophenol
2,4-Difluorothiophenol (CAS: 1996-44-7) is a fluorinated organic compound with the molecular formula C6H4F2S and a molecular weight of 146.16 g/mol. This thiol derivative is a valuable building block in organic synthesis, particularly for introducing fluorinated aromatic moieties into complex molecules. Its specific structure makes it useful in the development of pharmaceuticals, agrochemicals, and advanced materials. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- 2,4-Difluorobenzenethiol
- Synonyms
- 2,4-Difluorobenzenethiol1996-44-7

Pharmaceutical Intermediate
2,4-Difluorothiophenol serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its difluorinated phenyl ring can be incorporated to enhance metabolic stability, lipophilicity, or binding affinity of drug candidates.
Agrochemical Synthesis
This compound is employed in the creation of novel agrochemicals, such as herbicides, fungicides, and insecticides. The presence of fluorine atoms can influence the biological activity and environmental persistence of the final agrochemical product.
Materials Science
It finds application in the development of advanced materials, including polymers and liquid crystals. The unique electronic properties conferred by the fluorine substituents can be leveraged to tailor material characteristics for specific technological applications.
Research and Development
As a versatile fluorinated building block, 2,4-Difluorothiophenol is widely used in academic and industrial research laboratories for exploring new synthetic pathways and discovering novel chemical entities.
| Molecular weight | 146.16 |
|---|---|
| Empirical formula | C6H4F2S |
| Assay | 97% |
| Boiling point | 59 °C/20 mmHg(lit.) |
| Density | 1.29 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5235(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 49 °C / 120.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorothiophenol used for?
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2,4-Difluorothiophenol (CAS: 1996-44-7) is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It is also utilized in research and development laboratories.
What are the CAS number and formula for 2,4-Difluorothiophenol?
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The CAS number for 2,4-Difluorothiophenol is 1996-44-7, and its molecular formula is C6H4F2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorothiophenol with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,4-Difluorothiophenol be handled safely?
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2,4-Difluorothiophenol is a flammable liquid and vapour (H226). Handle with care, ensuring adequate ventilation and using appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., type ABEK respirator filter). Keep away from heat, hot surfaces, sparks, open flames, and other ignition sources.
Is 2,4-Difluorothiophenol typically shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,4-Difluorothiophenol. We can arrange for its shipment and export to various international destinations, adhering to all necessary regulations.
How can I request a sample or quote for 2,4-Difluorothiophenol?
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To request a sample or a quote for 2,4-Difluorothiophenol, please contact our sales team through the website or by calling our main office. Please provide your contact details and the required quantity.
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