PD-180970
PD-180970 (CAS 287204-45-9) is a chemical compound with the molecular formula C21H15Cl2FN4O and a molecular weight of 429.27 g/mol. This yellow solid, with a purity of ≥98% (HPLC), is primarily utilised in research settings. It serves as a valuable tool in cell biology, cell signalling, and neuroscience research, particularly in studies related to kinase and phosphatase biology, and non-receptor tyrosine kinases.
- IUPAC
- 6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one,PF-1515965
- Synonyms
- 6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one,PF-1515965
Cell Biology Research
PD-180970 is employed in cell biology research to investigate cellular processes and signalling pathways. Its role in kinase biology makes it a relevant compound for studying cell growth and differentiation.
Neuroscience Investigations
In neuroscience, this compound aids in the study of cell signalling pathways relevant to neurological functions. It is particularly useful for exploring non-receptor tyrosine kinase activity in neuronal cells.
Kinase Inhibitor Studies
As a non-receptor tyrosine kinase inhibitor, PD-180970 is a key reagent for researchers studying the role of these kinases in various biological processes and disease states.
Drug Discovery and Development
This compound is identified as an approved therapeutic or drug candidate, suggesting its potential application in preclinical drug discovery and development programmes.
| Molecular weight | 429.27 |
|---|---|
| Empirical formula | C21H15Cl2FN4O |
| Assay | ≥98% (HPLC) |
| Colour | yellow |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD-180970 used for?
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PD-180970 is used in cell biology, cell signalling, neuroscience, and kinase/phosphatase biology research, including studies on non-receptor tyrosine kinases and as a drug candidate.
What is the CAS number and formula for PD-180970?
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The CAS number is 287204-45-9, and the empirical formula is C21H15Cl2FN4O.
What grade and purity does Tech Serve Solutions supply for PD-180970?
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Tech Serve Solutions supplies PD-180970 with a purity of ≥98% (HPLC). We do not represent this product as USP, EP, or BP grade.
How should PD-180970 be handled safely?
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PD-180970 is classified as acutely toxic if swallowed (H301) and may cause prolonged adverse effects to aquatic life (H413). Handle with extreme caution, using appropriate personal protective equipment. In case of accidental ingestion, seek immediate medical attention. Refer to the Safety Data Sheet (SDS) for comprehensive handling and disposal information.
How is PD-180970 shipped and exported?
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PD-180970 is shipped and exported according to international regulations for hazardous materials, specifically UN 2811, Class 6.1, Packing Group III. Storage is recommended at 2-8°C.
How can I request a sample or quote for PD-180970?
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To request a sample or quote for PD-180970, please contact our sales team via the website or directly by phone or email, providing your specific requirements.
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