Celastrol

CAS 34157-83-0C29H38O4Cell Biology

Celastrol (CAS: 34157-83-0) is a triterpenoid with the molecular formula C29H38O4. This red solid, weighing 450.61 g/mol, is recognized for its potent antioxidant and cytoprotective properties. It finds application in various research areas, including cell biology, cell signaling, and the study of cellular stress, particularly in relation to nitric oxide pathways and nutrition research. Its role as a phytochemical is also of significant interest.

IUPAC: 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid,Tripterin
Synonyms: Tripterin10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid

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Celastrol (C29H38O4) — chemical structure, CAS 34157-83-0; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyCell StressNitric Oxide and Cell StressNutrition Research

01 /Applications

Antioxidant and Cytoprotective Research

Celastrol is employed in studies investigating cellular defence mechanisms against oxidative stress. Its capacity to scavenge free radicals and protect cells from damage is a key area of research.

Cell Biology and Signaling Investigations

This compound serves as a valuable tool for researchers exploring cellular processes, including cell signaling pathways and responses to cellular stress. It is utilized in studies related to neuroscience and cell viability.

Phytochemical and Traditional Medicine Studies

As a prominent phytochemical, Celastrol is studied for its potential biological activities derived from traditional sources. Research often focuses on its presence in herbal medicines and its mechanisms of action.

Nutrition Research

Celastrol's role in metabolic pathways and its impact on cellular energy and nutrient sensing are subjects of investigation within nutrition research.

02 /Properties

Molecular weight	450.61
Empirical formula	C29H38O4
Assay	≥98% (HPLC)
Form	solid
Colour	red
Solubility	DMSO: >10 mg/mLH2O: insoluble
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	2
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

34157-83-0

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Celastrol used for?

Celastrol is primarily used in scientific research as an antioxidant and cytoprotective agent. It is studied in the fields of cell biology, cell signaling, neuroscience, cell stress, and nutrition research, and is also of interest as a phytochemical from traditional medicine.

What is the CAS number and formula for Celastrol?

The CAS number for Celastrol is 34157-83-0, and its molecular formula is C29H38O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Celastrol with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Celastrol be handled safely?

Celastrol is classified as Danger (GHS06) with hazard statement H301 (Toxic if swallowed). Appropriate personal protective equipment includes eyeshields, faceshields, gloves, and a type P2 respirator cartridge. Handle with extreme caution and follow all safety recommendations.

How is Celastrol stored and shipped?

Celastrol should be stored at -20°C. It is shipped as a solid and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for hazardous materials (UN 2811 6.1 / PGIII).

How can I request a sample or quote for Celastrol?

To request a sample or a quotation for Celastrol, please contact our sales team via the website or by phone. Our experts are available to assist with your research needs.