Catharanthine
Catharanthine (CAS: 2468-21-5), a complex indole alkaloid with the molecular formula C21H24N2O2, is a valuable research chemical. It serves as a key precursor and intermediate in the synthesis of various biologically active compounds, notably vinca alkaloids. Its applications are primarily within cell biology research, focusing on cell signaling, neuroscience, and the cytoskeleton, particularly concerning microtubule dynamics.
- IUPAC
- (2α,5β,6α,18β)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester,7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester
Precursor in Alkaloid Synthesis
Catharanthine is a crucial intermediate in the total synthesis of vinca alkaloids, such as vinblastine and vincristine, which are important anti-cancer agents. Its unique indole structure is fundamental for building these complex molecules.
Cell Biology Research Tool
Utilised in cell biology studies, Catharanthine helps researchers investigate cellular processes related to cell signaling, neuroscience, and the cytoskeleton. Its interaction with microtubules makes it relevant for studying cell division and structure.
Microtubule Inhibitor Studies
As a compound related to microtubule inhibitors, Catharanthine aids research into the mechanisms of microtubule assembly and disassembly. This is vital for understanding cell motility, intracellular transport, and cell cycle progression.
| Molecular weight | 336.43 |
|---|---|
| Empirical formula | C21H24N2O2 |
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble5 mg/mL (clear solution; warmed) |
| Optical activity | [α]/D +30 to +38° (c=0.5, CDCl3) |
| Storage temperature | −20°C |
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Catharanthine primarily used for?
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Catharanthine (CAS: 2468-21-5) is primarily used as a key intermediate in the synthesis of vinca alkaloids and as a research tool in cell biology, particularly for studies involving cell signaling, neuroscience, and microtubule dynamics.
What are the CAS number and molecular formula for Catharanthine?
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The CAS number for Catharanthine is 2468-21-5, and its molecular formula is C21H24N2O2.
What grade and purity does Tech Serve Solutions supply for Catharanthine?
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Tech Serve Solutions supplies Catharanthine with an assay of ≥95% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Catharanthine be handled and stored?
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Catharanthine (CAS: 2468-21-5) has a WGK Germany rating of 3, indicating it is a substance of high danger to water. It should be stored at -20°C and handled with appropriate personal protective equipment in a well-ventilated area, avoiding release into the environment.
How is Catharanthine shipped by Tech Serve Solutions?
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Catharanthine is shipped by Tech Serve Solutions packed in wet ice to maintain its stability during transit and export.
How can I request a sample or quote for Catharanthine?
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To request a sample or quote for Catharanthine, please contact our sales team through the website or by phone, providing your specific requirements.
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