Celecoxib
Celecoxib (CAS: 169590-42-5), with the molecular formula C17H14F3N3O2S and a molecular weight of 381.37 g/mol, is supplied by Tech Serve Solutions as a white to off-white powder. This compound is recognised for its role in inhibiting cyclooxygenase enzymes. It finds primary application in research settings related to inflammation and pain pathways, serving as a valuable tool in biochemical and pharmacological studies.
- IUPAC
- 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide,CJ-016377,CP-598107,PF-00345549,PHA-00846533,SC-58635,YM-177
- Synonyms
- 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamideSC-58635PF-00345549YM-177CJ-016377CP-598107PHA-00846533
Biochemical Research
Celecoxib is used as a selective COX-2 inhibitor in biochemical and cell biology research to investigate inflammatory pathways and prostaglandin synthesis. Its specific action allows researchers to study the distinct roles of COX isoforms.
Pharmacological Studies
This compound serves as a reference standard and research tool in pharmacological studies focusing on non-steroidal anti-inflammatory drugs (NSAIDs) and their mechanisms of action. It aids in understanding drug interactions and developing new therapeutic agents.
Drug Discovery
Celecoxib is employed in drug discovery programs, particularly in the development of novel anti-inflammatory and analgesic agents. Its known inhibitory profile provides a benchmark for evaluating new chemical entities.
| Molecular weight | 381.37 |
|---|---|
| Empirical formula | C17H14F3N3O2S |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H360D
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 60-61-52 |
| Safety statements (S) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Celecoxib used for?
+
Celecoxib is used in biochemical and pharmacological research, particularly as a selective COX-2 inhibitor for studying inflammatory pathways and in drug discovery programs.
What is the CAS number and formula for Celecoxib?
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The CAS number for Celecoxib is 169590-42-5, and its empirical formula is C17H14F3N3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Celecoxib with a purity of ≥98% (HPLC). This product is intended for research and laboratory use only and is not supplied as USP, BP, or EP grade.
How should Celecoxib be handled safely?
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Celecoxib is classified with a GHS08 symbol and 'Danger' signal word, with hazard statement H360D (May damage the unborn child). Handle with extreme caution, using appropriate personal protective equipment (P201, P308 + P313) and avoiding exposure, particularly if pregnant or planning pregnancy.
Is Celecoxib a controlled substance?
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The provided data does not indicate that Celecoxib is a controlled substance. However, users should always consult local regulations regarding its handling and use.
How is Celecoxib packed and shipped?
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Celecoxib is typically supplied as a white to off-white powder and is shipped at room temperature. For export, it is classified under UN 3077, Class 9, Packing Group III.
How can I request a sample or quote for Celecoxib?
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To request a sample or quote for Celecoxib, please contact our sales department through the website or by phone, providing the product name and CAS number (169590-42-5).
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