(1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride
(1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride (CAS: 1052707-21-7) is a chiral diamine salt with a molecular weight of 444.27 g/mol. This compound is primarily utilised as a key building block and ligand in asymmetric synthesis. Its specific stereochemistry makes it valuable for developing enantioselective catalytic processes, enabling the production of chiral molecules with high optical purity. Tech Serve Solutions supplies this reagent for advanced chemical research and development.
- IUPAC
- (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride
- Synonyms
- 1052707-21-7C18H26N4 · 4HCl(1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride

Asymmetric Catalysis
This chiral diamine acts as a ligand or catalyst precursor in asymmetric synthesis. It is employed to induce enantioselectivity in various organic transformations, leading to the preferential formation of one enantiomer over the other.
Chiral Building Block
As a well-defined chiral molecule, it serves as a valuable building block for the synthesis of complex chiral targets in pharmaceuticals and fine chemicals. Its stereocenters can be incorporated into larger molecular structures.
Ligand Development
The compound's structure, featuring two coordinating amine groups and specific stereochemistry, makes it suitable for developing novel chiral ligands for transition metal catalysis.
| Molecular weight | 444.27 |
|---|---|
| Empirical formula | C18H26N4 · 4HCl |
| Assay | 97% |
| Optical activity | [α]22/D -38.0°, c = 1 in H2O |
| Melting point | 209-225 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride used for?
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(1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride is primarily used in asymmetric synthesis as a chiral building block and as a ligand or catalyst precursor in enantioselective catalysis.
What is the CAS number and formula for this compound?
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The CAS number is 1052707-21-7, and its empirical formula is C18H26N4 · 4HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This is a research-grade material and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, faceshields, and gloves, should be used. Ensure adequate ventilation and avoid breathing dust.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled.
How is this product packed and exported?
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Products are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a sample or quote?
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Please contact our sales team via the website to request a sample or obtain a quotation for (1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride.
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