(1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine
(1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine (CAS: 212555-28-7) is a chiral diamine derivative with a molecular weight of 422.56. It serves as a valuable building block and ligand in asymmetric synthesis, particularly in catalytic applications such as hydrogenation. This compound is essential for researchers and chemists engaged in stereoselective transformations and the development of chiral molecules.
- Synonyms
- 2-cyclohexanediamine, (CH3C6H4SO2NH)2C6H10

Asymmetric Synthesis
Utilised as a chiral ligand or auxiliary in stereoselective reactions, enabling the formation of enantiomerically enriched products. Its specific stereochemistry is key to directing the outcome of asymmetric transformations.
Catalysis
Functions as a component in chiral catalysts, facilitating enantioselective hydrogenation and other catalytic processes. It helps in the synthesis of chiral intermediates for pharmaceuticals and fine chemicals.
Chiral Building Block
Serves as a fundamental chiral starting material for the synthesis of more complex chiral molecules. Its defined stereocentres are incorporated into target structures.
Ligand Development
Investigated and employed in the design and synthesis of novel chiral ligands for metal-catalyzed reactions, aiming to improve selectivity and efficiency.
| Molecular weight | 422.56 |
|---|---|
| Linear formula | (CH3C6H4SO2NH)2C6H10 |
| Assay | 98% |
| Optical activity | [α]22/D −3°, c = 2.33 in pyridine |
| Melting point | 170-173 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine used for?
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This compound is primarily used in asymmetric synthesis as a chiral building block, ligand, or catalyst component, particularly for enantioselective hydrogenation and other stereoselective reactions.
What are the CAS number and formula for this chemical?
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The CAS number is 212555-28-7 and the linear formula is (CH3C6H4SO2NH)2C6H10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine with an assay of 98%. This is a research-grade chemical and is not supplied as USP, BP, EP, or for pharmaceutical use.
How should I safely handle (1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation, wear protective gloves and eye protection, and avoid breathing dust. If in eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do.
How is (1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine packed, shipped, and exported?
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Products are packed securely in accordance with international shipping regulations. Tech Serve Solutions is a global supplier and exporter experienced in handling and shipping fine chemicals worldwide.
How can I request a sample or a quote for (1S,2S)-(−)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine?
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Please use the 'Request a Quote' or 'Request a Sample' button on our website, or contact our sales team directly with your specific requirements.
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