(1S,2S)-(2-Amino-1-phenylpropyl)diphenylphosphine
(1S,2S)-(2-Amino-1-phenylpropyl)diphenylphosphine, CAS: 341968-71-6, is a chiral aminophosphine ligand with a molecular weight of 319.38 g/mol. This compound is crucial in asymmetric synthesis, serving as a building block for chiral catalysts. Its specific stereochemistry makes it valuable for controlling the enantioselectivity of various chemical transformations, enabling the synthesis of optically pure compounds vital in pharmaceuticals and fine chemicals. Tech Serve Solutions offers this high-quality reagent for advanced chemical research and development.
- IUPAC
- (1S,2S)-(2-Diphenylphosphino)-1-methyl-2-phenylethylamine
- Synonyms
- (1S,2S)-(2-Diphenylphosphino)-1-methyl-2-phenylethylamine
Asymmetric Catalysis
This phosphine ligand is employed in the development of chiral catalysts for asymmetric hydrogenation, hydroformylation, and other stereoselective reactions. It enables the efficient synthesis of enantiomerically enriched products.
Chiral Ligand Synthesis
As a versatile building block, it is used in the construction of more complex chiral ligands and organometallic complexes. These advanced materials are critical for achieving high enantioselectivity in catalytic processes.
Pharmaceutical Intermediate Synthesis
Its stereospecific nature makes it invaluable for the synthesis of chiral pharmaceutical intermediates, where precise control over stereochemistry is paramount for drug efficacy and safety.
| Molecular weight | 319.38 |
|---|---|
| Empirical formula | C21H22NP |
| Optical activity | [α]22/D +116°, c = 0.5 in chloroform |
| Melting point | 100-105 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Transport (UN / ADR) | UN 3335 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(2-Amino-1-phenylpropyl)diphenylphosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, facilitating the production of enantiomerically pure compounds, particularly in pharmaceutical and fine chemical manufacturing.
What is the CAS number and formula for this compound?
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The CAS number is 341968-71-6, and its empirical formula is C21H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a high-purity research-grade reagent. We do not represent it as USP, BP, or EP grade. Please refer to the product specifications for assay details.
How should (1S,2S)-(2-Amino-1-phenylpropyl)diphenylphosphine be handled safely?
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This compound is classified as irritating to the eyes, skin, and respiratory system (H315, H319, H335). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Wear suitable eye protection and protective gloves.
Is this product a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions specialises in global export and adheres to all international shipping regulations for chemicals. Specific packaging and shipping details will be provided upon inquiry.
How can I request a sample or quote?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (341968-71-6).
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