5-Amino-2-(trifluoromethyl)pyridine
5-Amino-2-(trifluoromethyl)pyridine (CAS 106877-33-2), with the molecular formula C6H5F3N2 and a molecular weight of 162.11 g/mol, is a valuable heterocyclic building block. This compound is notably employed in the convenient, one-pot synthesis of azaindoles. It serves as a key intermediate in chemical synthesis, offering a specific structural motif for further derivatization in research and development.
Synthesis of Azaindoles
This pyridine derivative is a crucial reagent for the efficient, one-pot synthesis of azaindole structures. Its specific reactivity facilitates the construction of these important heterocyclic scaffolds.
Chemical Synthesis Intermediate
Utilised as a building block in organic synthesis, 5-Amino-2-(trifluoromethyl)pyridine offers a trifluoromethyl-substituted pyridine core. This allows for the introduction of fluorinated pyridine moieties into larger, more complex molecules.
Research and Development
Serves as a versatile intermediate for researchers exploring novel compounds with potential applications in pharmaceuticals and materials science. Its unique structural features are valuable for creating diverse chemical libraries.
| Molecular weight | 162.11 |
|---|---|
| Empirical formula | C6H5F3N2 |
| Assay | 96% |
| Application | Employed in a covenient, one-pot, synthesis of azaindoles.1 |
| Melting point | 39-43 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/38-43 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-2-(trifluoromethyl)pyridine primarily used for?
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It is primarily used as a building block in chemical synthesis, notably for the one-pot synthesis of azaindoles.
What are the CAS number and molecular formula for 5-Amino-2-(trifluoromethyl)pyridine?
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The CAS number is 106877-33-2 and the molecular formula is C6H5F3N2.
What grade and purity does Tech Serve Solutions supply for 5-Amino-2-(trifluoromethyl)pyridine?
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Tech Serve Solutions supplies 5-Amino-2-(trifluoromethyl)pyridine with a minimum purity of 96%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 5-Amino-2-(trifluoromethyl)pyridine be handled safely?
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This compound is classified as toxic if swallowed and causes skin and serious eye irritation, as well as allergic skin reactions. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge, in a well-ventilated area. Refer to the safety data sheet for full handling instructions.
Can Tech Serve Solutions export 5-Amino-2-(trifluoromethyl)pyridine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Amino-2-(trifluoromethyl)pyridine.
How can I request a quote or sample for 5-Amino-2-(trifluoromethyl)pyridine?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through the website or by direct inquiry, referencing the product name and CAS number.
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