(1S,2S)-(+)-trans-1-Amino-2-indanol
(1S,2S)-(+)-trans-1-Amino-2-indanol (CAS: 163061-74-3) is a chiral amino alcohol with a molecular weight of 149.19 g/mol. This compound is a valuable building block in asymmetric synthesis, primarily utilised for the preparation of chiral ligands and catalysts. Its specific stereochemistry makes it essential for stereoselective reactions, contributing to the efficient synthesis of enantiomerically pure compounds in research and development across various chemical disciplines.
- Synonyms
- C9H11NO
Chiral Auxiliary in Asymmetric Synthesis
This amino alcohol serves as a chiral auxiliary, enabling stereoselective control in various organic transformations. Its defined stereocentres are crucial for inducing enantioselectivity in reactions like alkylations and reductions.
Ligand Synthesis
It is used in the preparation of chiral ligands for transition metal catalysis. These ligands are vital for promoting enantioselective versions of important reactions such as hydrogenations and C-C bond formations.
Precursor for Pharmaceutical Intermediates
The chiral nature of (1S,2S)-(+)-trans-1-Amino-2-indanol makes it a sought-after precursor for synthesising complex, enantiomerically pure pharmaceutical intermediates where specific stereochemistry is critical for biological activity.
Research and Development
Employed in academic and industrial research laboratories for exploring new synthetic methodologies and developing novel chiral compounds. Its availability aids in the discovery of new chemical entities and advanced materials.
| Molecular weight | 149.19 |
|---|---|
| Empirical formula | C9H11NO |
| Assay | 97% |
| Optical activity | [α]/D +23.0°, c = 1 in ethanol |
| Melting point | 142-146 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(+)-trans-1-Amino-2-indanol primarily used for?
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(1S,2S)-(+)-trans-1-Amino-2-indanol is predominantly used as a chiral building block in asymmetric synthesis, particularly for the preparation of chiral ligands and as a chiral auxiliary in stereoselective reactions.
What are the CAS number and formula for (1S,2S)-(+)-trans-1-Amino-2-indanol?
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The CAS number is 163061-74-3, and the empirical formula is C9H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S,2S)-(+)-trans-1-Amino-2-indanol with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (1S,2S)-(+)-trans-1-Amino-2-indanol be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. This compound is classified as a Warning, causing skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335).
Is (1S,2S)-(+)-trans-1-Amino-2-indanol a controlled substance?
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The provided data does not indicate that (1S,2S)-(+)-trans-1-Amino-2-indanol is a controlled substance.
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transportation. Specific packing details are available upon request.
How can I request a sample or a quote for (1S,2S)-(+)-trans-1-Amino-2-indanol?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (163061-74-3).
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