(1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine
(1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine (CAS: 167316-27-0) is a chiral diamine derivative with a molecular weight of 366.48 g/mol. It serves as a valuable building block in asymmetric synthesis and as a ligand or reagent in chiral catalysis. Its specific stereochemistry makes it useful for creating enantiomerically pure compounds in various chemical synthesis applications. This compound is typically supplied at a high purity for demanding research and development projects.
- Synonyms
- 167316-27-0CH3C6H4SO2NHCH(C6H5)CH(C6H5)NH2

Chiral Ligand in Asymmetric Catalysis
This diamine derivative is employed as a chiral ligand in metal-catalyzed asymmetric reactions. It facilitates the enantioselective synthesis of complex organic molecules by inducing chirality during the catalytic process.
Building Block for Chiral Synthesis
Its defined stereochemistry makes it a crucial chiral building block for constructing enantiomerically pure pharmaceuticals, agrochemicals, and advanced materials. It can be incorporated into larger molecular frameworks.
Reagent in Organic Synthesis
Used as a specialized reagent in various organic transformations, particularly where stereochemical control is paramount. Its structure allows for participation in a range of reactions.
Hydrogenation Reactions
This compound finds application in asymmetric hydrogenation processes, contributing to the efficient and enantioselective reduction of prochiral substrates.
| Molecular weight | 366.48 |
|---|---|
| Linear formula | CH3C6H4SO2NHCH(C6H5)CH(C6H5)NH2 |
| Assay | 98% |
| Optical activity | [α]20/D +35°, c = 1 in chloroform |
| Melting point | 128-131 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis, a chiral building block in organic synthesis, and as a reagent in hydrogenation reactions. It is valuable for creating enantiomerically pure compounds.
What are the CAS number and formula for this compound?
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The CAS number is 167316-27-0. The linear formula is CH3C6H4SO2NHCH(C6H5)CH(C6H5)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as a Warning (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine packed, shipped, and exported?
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Tech Serve Solutions offers secure and compliant packaging suitable for export. We adhere to all international shipping regulations for chemical substances.
How can I request a sample or a quote?
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To request a sample or a quote for (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine, please contact our sales department via the website or direct inquiry.
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