(1S,2S)-(+)-N-Methylpseudoephedrine

CAS 51018-28-1C6H5CH[CH(CH3)N(CH3)2]OHChemical Synthesis

(1S,2S)-(+)-N-Methylpseudoephedrine (CAS: 51018-28-1) is a chiral organic compound with a molecular weight of 179.26 g/mol. This ephedrine derivative serves as a valuable tool in asymmetric synthesis and chemical research. Its specific stereochemistry makes it particularly useful as a chiral auxiliary in various stereoselective reactions, aiding in the synthesis of enantiomerically pure compounds. It is also investigated for applications in cell biology and nutritional research.

IUPAC: (+)-N-Methylpseudoephedrine,(1S,2S)-2-Dimethylamino-1-phenylpropanol
Synonyms: (+)-N-Methylpseudoephedrine(1S,2S)-2-Dimethylamino-1-phenylpropanol2-Dimethylamino-1-phenylpropan-1-ol, (1S,2S)-1-Phenyl-2-(dimethylamino)-1-propanol, (1S,2S)-

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(1S,2S)-(+)-N-Methylpseudoephedrine (C6H5CH[CH(CH3)N(CH3)2]OH) — chemical structure, CAS 51018-28-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisCell BiologyChemical SynthesisChiral AuxiliariesEphedra sinicaEphedrine DerivativesNutrition Research

01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

As a chiral auxiliary, (1S,2S)-(+)-N-Methylpseudoephedrine can be used to induce stereoselectivity in chemical reactions. This enables the synthesis of specific enantiomers, which is crucial for pharmaceuticals and fine chemicals where stereochemistry dictates biological activity.

Research in Stereoselective Reactions

The compound is employed in academic and industrial research settings to explore and develop new stereoselective methodologies. Its well-defined stereochemistry facilitates the study of reaction mechanisms and the optimization of chiral induction.

Building Block in Organic Synthesis

It can serve as a chiral building block for the construction of more complex molecules. Its structure, featuring amine and alcohol functionalities along with defined stereocenters, offers versatile synthetic possibilities.

Investigation in Cell Biology

Related ephedrine derivatives have been studied for their biological effects. (1S,2S)-(+)-N-Methylpseudoephedrine may be used in research to understand cellular processes or as a reference compound.

02 /Properties

Molecular weight	179.26
Linear formula	C6H5CH[CH(CH3)N(CH3)2]OH
Assay	99%
Boiling point	145 °C/24 mmHg(lit.)
Optical activity	[α]21/D +48°, c = 5 in methanol
Storage temperature	2-8°C
Melting point	29-31 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Flash point	113 °C / 235.4 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22-36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51018-28-1

MDL number

MFCD00064260

PubChem substance

24857422

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1S,2S)-(+)-N-Methylpseudoephedrine used for?

(1S,2S)-(+)-N-Methylpseudoephedrine is primarily used as a chiral auxiliary in asymmetric synthesis and as a research chemical for stereoselective reactions. It may also find applications in cell biology and nutritional research.

What is the CAS number and chemical formula for (1S,2S)-(+)-N-Methylpseudoephedrine?

The CAS number is 51018-28-1 and the linear formula is C₆H₅CH[CH(CH₃)N(CH₃)₂]OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (1S,2S)-(+)-N-Methylpseudoephedrine with a minimum assay of 99%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling precautions for (1S,2S)-(+)-N-Methylpseudoephedrine?

This compound is a Warning substance, with hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Always use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. It is classified as WGK 3 in Germany.

How is (1S,2S)-(+)-N-Methylpseudoephedrine shipped and exported?

Tech Serve Solutions, as a global supplier and exporter, ships and exports (1S,2S)-(+)-N-Methylpseudoephedrine in compliance with all relevant international and national regulations for chemical transport.

How can I request a sample or quote for (1S,2S)-(+)-N-Methylpseudoephedrine?

To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (51018-28-1).